Table 2 Summary of findings table for presenting risks and quality of evidence about recruited studies
From: Secnidazole for treatment of bacterial vaginosis: a systematic review
One gr Secnidazole compared to placebo for bacterial vaginosis Bibliography: secnidazole for bacterial vaginosis. Cochrane Database of Systematic Reviews [Year], Issue [Issue]. | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Certainty assessment | Summary of findings | ||||||||||
№ of participants (studies) Follow-up | Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | Overall certainty of evidence | Study event rates (%) | Relative effect (95% CI) | Anticipated absolute effects | ||
With placebo | With 1 g Secnidazole | Risk with placebo | Risk difference with 1 g Secnidazole | ||||||||
clinical cure rate | |||||||||||
126 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 11/62 (17.7%) | 33/64 (51.6%) | RR 2.92* (1.64 to 5.19) | 177 per 1000 | 341 more per 1000 (from 114 more to 743 more) |
clinical cure rate - Clinical cure of pts. with 3 or less episodes of BV in the last year | |||||||||||
87 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 10/43 (23.3%) | 26/44 (59.1%) | RR 2.54* (1.40 to 4.61) | 233 per 1000 | 358 more per 1000 (from 93 more to 840 more) |
clinical cure rate - Clinical cure of pts. with 4 or more episodes of BV in the last year | |||||||||||
39 (1 RCT) | not serious | not serious | not serious | very serious a | none | ⨁⨁ ◯◯ LOW | 1/19 (5.3%) | 7/20 (35.0%) | RR 6.65 (0.90 to 49.09) | 53 per 1000 | 297 more per 1000 (from 5 fewer to 1000 more) |
Microbiologic cure rate | |||||||||||
126 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 4/62 (6.5%) | 15/64 (23.4%) | RR 3.35* (1.26 to 8.95) | 65 per 1000 | 152 more per 1000 (from 17 more to 513 more) |
Microbiologic cure rate - Microbiologic cure of pts. with 3 or less episodes of BV in the last year | |||||||||||
87 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 4/43 (9.3%) | 13/44 (29.5%) | RR 3.18* (1.12 to 8.98) | 93 per 1000 | 203 more per 1000 (from 11 more to 742 more) |
Therapeutic cure rate | |||||||||||
126 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 4/62 (6.5%) | 14/64 (21.9%) | RR 3.14* (1.17 to 8.42) | 65 per 1000 | 138 more per 1000 (from 11 more to 479 more) |
Therapeutic cure rate - Therapeutic cure of pts. with 3 or less episodes of BV in the last year | |||||||||||
87 (1 RCT) | not serious | not serious | not serious | not serious | none | ⨁⨁⨁⨁ HIGH | 4/43 (9.3%) | 13/44 (29.5%) | RR 3.18* (1.12 to 8.98) | 93 per 1000 | 203 more per 1000 (from 11 more to 742 more) |
Therapeutic cure rate - Therapeutic cure of pts. with 4 or more episodes of BV in the last year | |||||||||||