Table 1 Characteristics of women with LS during endometrial surveillance by tampons and subsequent endometrial sampling (n = 25)
From: Feasibility of endometrial sampling by vaginal tampons in women with Lynch syndrome
|  | Overall (n = 25) | Premenopausal women (n = 15) | Postmenopausal women (n = 10) |
|---|---|---|---|
Age at study entry, mean (SD) in years | 48.8 (9.9) | 42.8 (4.3) | 57.9 (9.0) |
Age at study entry, median (range) in years | 47.0 (73–71) | 42.0 (37–50) | 56.0 (46–71) |
Gene mutation | |||
MLH1 | 3 (12%) | 2 (13%) | 1 (10%) |
MSH2 | 5 (20%) | 3 (20%) | 2 (20%) |
MSH6 | 6 (24%) | 5 (33%) | 1 (10%) |
PMS2 | 5 (20%) | 2 (13%) | 3 (30%) |
 Lynch | 1 (4%) | – | 1 (10%) |
 First degree relative LS | 5 (20%) | 3 (20%) | 2 (20%) |
Menopausal state | |||
 Premenopausal | 15 (60%) | 15 (100%) | Naa |
 Postmenopausal | 10 (40%) | Naa | 10 (100%) |
Parity | |||
 Nulliparous | 4 (20%) | 2 (13%) | 2 (40%) |
 Primi/multiparous | 16 (80%) | 13 (87%) | 3 (60%) |
 Unknown | 5 |  | 5 |
Hormonal treatment | |||
 OC | 3 (12%) | 3 (20%) | – |
 Mirena IUD | 5 (20%) | 4 (27%) | 1 (10%) |
 Progesterone | 1 (4%) | 1 (7%) | – |
 HRTb | 1 (4%) | – | 1 (10%) |
 None | 15 (60%) | 7 (47%) | 8 (80%) |
Endometrial response (mm), Median (range) | 3.8 (1–18) | 4.5 (2–18) | 3.0 (1–7) |
 1–2 | 3 (13%) | 1 (6%) | 2 (22%) |
  > 2–4 | 9 (38%) | 6 (40%) | 3 (33%) |
  > 4–6 | 5 (21%) | 2 (13%) | 3 (33%) |
  > 6–8 | 1 (4%) | – | 1 (11%) |
  > 8–10 | 2 (8%) | 2 (13%) | – |
  > 10 | 4 (17%) | 4 (27%) | – |
 Unknown | 1 | – | 1 |
Last period | |||
  - < 2 weeks | 3 (12%) | 3 (21%) | – |
  - ≥ 2 weeks | 11 (46%) | 11 (79%) | – |
Postmenopausal | 10 (42%) | – | 10 (100%) |
 Unknown | 1 | 1 | – |