Table 3 Association between mitochondrial DNA copy number and cervical cancer
Variables | Quartiles of mtCN a | Ptrend | Pinteractionc | |||
|---|---|---|---|---|---|---|
1st quartile | 2nd quartile | 3rd quartile | 4th quartile | |||
Reference | OR (95% CI) b | OR (95% CI) b | OR (95% CI) b | |||
Age (years) | ||||||
 < 50 | 1.00 | 0.87(0.49–1.55) | 1.25(0.74–2.10) | 1.44(0.87–2.40) | 0.08 | 0.40 |
 ≥ 50 | 1.00 | 1.14(0.61–2.16) | 2.10(1.10–4.02) | 2.32(1.24–4.35) | 0.002 | |
HPV16 | ||||||
 Negative | 1.00 | 1.10(0.67–1.89) | 2.09(1.26–3.46) | 2.03(1.23–3.33) | 0.001 | 0.21 |
 Positive | 1.00 | 1.00(0.55–2.10) | 0.79(0.40–1.57) | 1.56(0.77–3.16) | 0.34 | |
HPV18 | ||||||
 Negative | 1.00 | 1.08(0.74–1.68) | 1.57(1.02–2.41) | 1.67(1.10–2.53) | 0.01 | 0.26 |
 Positive | 1.00 | 0.56(0.26–2.47) | 1.30(0.38–4.50) | 2.97(0.77–11.38) | 0.07 | |
HPV52 | ||||||
 Negative | 1.00 | 0.97(0.71–1.55) | 1.46(0.93–2.3) | 1.88(1.21–2.92) | 0.002 | 0.77 |
 Positive | 1.00 | 1.31(0.44–3.43) | 1.85(0.71–4.8) | 1.67(0.65–4.28) | 0.24 | |
HPV58 | ||||||
 Negative | 1.00 | 1.04(0.73–1.62) | 1.54(1.00–2.37) | 1.71(1.12–2.61) | 0.003 | 0.65 |
 Positive | 1.00 | 0.58(0.27–2.44) | 1.65(0.50–5.49) | 2.15(0.69–6.67) | 0.08 | |
Others | ||||||
 Negative | 1.00 | 1.22(0.66–2.12) | 1.14(0.68–1.90) | 1.80(1.10–2.96) | 0.03 | 0.25 |
 Positive | 1.00 | 0.81(0.57–1.63) | 2.40(1.22–4.71) | 1.94(0.99–3.81) | 0.003 | |
Multiple infection | ||||||
 Negative | 1.00 | 1.10(0.74–1.71) | 1.57(1.03–2.39) | 1.82(1.21–2.74) | 0.001 | 0.25 |
 Positive | 1.00 | 0.26(0.16–1.82) | 1.07(0.18–6.37) | 1.11(0.19–6.56) | 0.42 | |