Independent risk factors for axillary lymph node metastasis in breast cancer patients with one or two positive sentinel lymph nodes

Table 2 Univariate logistic regression analysis of the relationship between sociodemographic, clinical, and pathological factors and ALN metastasis in breast cancer patients with one or two positive SLNs

	Parameter	β	SE	P	OR	95% CI
X1	Age	−0.5341	0.26	0.04	0.586	0.352–0.976
X2	Occupation	−0.2695	0.1221	0.0273	0.764	0.601–0.970
X3	Menarche	0.2967	0.233	0.2029	1.345	0.852–2.124
X4	Menopausal status	−0.00174	0.2056	0.9933	0.998	0.667–1.494
X5	Delay in diagnosis (days)	−0.00233	0.086	0.9784	0.998	0.843–1.181
X6	Tumor primary site	0.3760	0.2048	0.0664	1.457	0.975–2.176
X7	Tumor primary quadrant	−0.1329	0.1088	0.2218	0.876	0.707–1.084
X8	Tumor Size	−0.0365	0.2109	0.8626	0.964	0.638–1.458
X9	Pathology	0.1599	0.3748	0.6697	1.173	0.563–2.446
X10	ER	−0.0632	0.2547	0.804	0.939	0.570–1.546
X11	PR	−0.0323	0.2209	0.8839	0.968	0.628–1.493
X12	HER2	−0.0487	0.2806	0.8621	0.952	0.549–1.651
X13	Triple negative	−0.1542	0.3865	0.69	0.857	0.402–1.828
X14	Ki-67	−0.0570	0.2503	0.8199	0.945	0.578–1.543
X15	Tumor grade	0.0994	0.1481	0.502	1.105	0.826–1.476
X16	Postoperative ALNs	−0.0632	0.089	0.4778	0.939	0.789–1.118
X17	Ratio of positive to total SLNs	0.9606	0.215	< 0.0001	2.613	1.715–3.983

Abbreviations: OR odds ratio, confidential interval, ER estrogen receptor, PR progesterone receptor, Her-2 human epidermal growth factor receptor-2, SLN sentinel lymph node, ALN axillary lymph node. To avoid missing any significant indicators, the factors with a significance of P < 0.05 in the univariate logistic regression analysis, including age, occupation, and the ratio of positive to the total number of SLNs were considered to entry into the multivariate logistic regression analysis