Prognostic factors for future mental, physical and urogenital health and work ability in women, 45–55 years: a six-year prospective longitudinal cohort study

Table 4 Prognostic factors for good health estimated by the SF36 subscales Role Function, Physical Function, Vitality and Social Function at 6 year follow-up

	RF n = 71 ≥ 84^a		PF n = 70 ≥ 86^a		VT n = 70 ≥ 68^a		SF n = 70 ≥ 88^a
Predictors	P-value	Effect size^b	P-value	Effect size^b	P-value	Effect size^b	P-value	Effect size^b
Age^c	0.60	1.06 (0.86–1.3)	1.0	1.0 (0.83–1.2)	0.12	1.3 (0.94–1.7)	0.078	0.12 (0.98–1.5)
Tertiary education	0.12	0.34 (0.089–1.3)	0.78	0.83 (0.22–3.1)	0.033	0.18 (0.035–0.87)	0.0051	0.12 (0.28–0.50)
Work ability^d	0.065	7.3 (0.89–59)	0.028	8.7 (1.3–61)	0.21	5.5 (0.39–80)	0.62	1.6 (0.24–11)
Living with a partner	0.016	32 (1.9–530)	0.87	1.2 (0.12–11)	0.60	0.47 (0.027–8.1)	0.031	21 (1.3–320)
Children at home	0.76	0.78 (0.16–3)	0.19	3.0 (0.59–15)	0.15	4.0 (0.61–26)	0.34	0.46 (0.91–2.3)
Depression^e	0.077	0.28 (0.065–1.2)	0.021	0.20 (0.050–0.78)	0.014	0.092 (0.014–0.61)	0.11	0.31 (0.072–1.3)
MRS symptoms
Somatic^f	0.51	0.45 (0.043–4.7)	0.96	0.96 (0.15–6.2)	0.47	2.6 (0.19–36)	0.23	0.25 (0.025–2.4)
Psychologic^f	0.45	0.56 (0.12–2).5)	0.88	1.1 (0.25–5.2)	1.0	0.00 (0.00-∞)	0.25	0.40 (0.085–1.9)
Urogenital^f	0.65	1.4 (0.32–6.2)	0.47	1.7 (0.42–6.6	0.64	1.5 (0.26–8.7)	0.29	0.46 (0.11–2.0)
Active intervention^g	0.059	3.0 (0.85–1.04)	0.14	2.6 (0.73–9.4)	0.10	3.4 (0.78–15)	0.065	0.31(0.87–1.1)
Nagelkirke R square		0.38		0.27		0.57		0.40
Hosmer-Lemeshow test	0.63		0.47		0.91		0.80
Area Under Curve^f	0.031	0.65 (0.52–0.78)	0.015	0.68 (0.54–0.81)	0.005	0.70 (0.58–0.83)	0.000	0.82 (0.72–0.91)
Omnibus test of model	0.009		0.12		< 0.001		0.006

^aCut of for norm Swedish women age 46–54 years, SF36. SF36 subscales; Role function (RF), Physical function (PF), Vitality (VT) and Social function (SF). Higher score indicated better health
^bEffect size is Odds Ratio and (95% CI) for all predictors. First figure is p-value, second figure is predicted probability and CI. The odds ratio increase in score value
^cOdds Ratio for an increase in age of 1 year between 45 and 55 years
^dWorking more than one hour/week
^eMontgomery-Asberg Depression Rating Scale (MADRS) score ≥ 7 indicating at least mild depression. Information is missing in 5 women (66/71)
^fMenopause Rating Scale and total Menopause Rating Scale (MRS) scoring. Somatic symptoms - hot flushes, heart discomfort, sleeping problems and muscle and joint problems; Psychological symptoms - depressive mood, irritability, anxiety and physical and mental exhaustion; Urogenital symptoms - sexual problems, bladder problems and vaginal dryness. Higher score indicates more severe symptoms
^gThe active group intervention is just as an adjustment and it is not the focus of this study