Table 1 The course of treatment for this Low-grade Endometrial Stromal Sarcoma case

a: 45 y 1 m

The tumor between liver and right diaphragm increased

TC^a, 7 cycles

SD

b: 45 y 9 m

The tumor between liver and right diaphragm increased

Ifosfamide + Doxorubicin^b, 3 cycles

PD

c: 45 y 11 m

The tumor between liver and right diaphragm increased

Proton therapy, 70.2 GyE/26 Fr. For 40 days

PR (Fig. 1)

d: 46 y 3 m

The tumors outside of the irradiation field remained

Surgery for the left pleural and abdominal tumors

Neuroendocrine carcinoma

e: 46 y 5 m

Thrombosis in inferior vena cava distal part

An inferior vena cava filter. Discontinued MPA^c.

Disappeared 11 months later.

f: 46 y 5 m

Small disseminations remained at the end of the surgery

^dCisplatin + Irinotecan, 4 cycles, every 4 weeks

PD

g: 46 y 8 m

Liver metastasis increased

Surgery for liver metastasis.

No remnant in surgical field

h: 46 y 11 m

Effective for small dissemination tumors

^dCisplatin + Irinotecan, 2 cycles, every 3 months

Discontinued by dehydration

i: 47 y 4 m

Multiple lung metastases recurred

TC^a, one cycle.

Discontinued by pneumothorax

j: 47 y 11 m

Abdominal and spleen dissemination increased

Splenectomy and dissemination resection

No remnant in surgical field

k: 48 y 1 m

Vaginal bleeding by recurrence in vaginal stump

Eribulin 1.4 mg/m², 3 cycles.

PD

l: 48 y 4 m

The tumors increased.

TC^a, 3 cycles

Hypersensitivity for carboplatin

m: 48 y 7 m

Discontinuation of carboplatin

Paclitaxel (140 mg/m²) 2 cycles

PD

n: 48 y 8 m

Jaundice and liver dysfunction

The common bile duct stents (Fig. 2).

Recovered liver dysfunction

o: 48 y 9 m

Liver metastasis increased

Pazopanib hydrochloride 800 mg/day started

SD to PD (Fig. 2)

p: 49 y 7 m

Bacterial infection from liver tumor via bile duct

Antibiotics and palliative care

Died with sepsis (Fig. 3)