Skip to main content

Table 4 Cognitive function around menopause with menopausal stage and number of previous testing occasions (N = 2402–2408)

From: Changes in six domains of cognitive function with reproductive and chronological ageing and sex hormones: a longitudinal study in 2411 UK mid-life women

 

Verbal episodic memory

Working memory

Processing speed

Verbal intelligence

Verbal fluency

Immediate logical memory

Delayed logical memory

Backward digit span

Digit symbol coding

Spot-the-word

Same letter word

SD difference (95% CI)

SD difference (95% CI)

SD difference (95% CI)

SD difference (95% CI)

SD difference (95% CI)

SD difference (95% CI)

Previous testing occasions

0.32 (0.25, 0.39)

0.39 (0.32, 0.46)

0.12 (0.06, 0.17)

0.24 (0.20, 0.28)

−0.02 (−0.06, 0.02)

0.14 (0.09, 0.18)

Menopausal stage

 Pre-menopause

(ref)

(ref)

(ref)

(ref)

(ref)

(ref)

 Peri-menopause

0.05 (−0.08, 0.19)

− 0.00 (− 0.13, 0.13)

−0.02 (− 0.13, 0.08)

−0.10 (− 0.18, − 0.03)

0.03 (− 0.05, 0.10)

0.08 (− 0.01, 0.16)

 Post-menopause

−0.09 (− 0.24, 0.06)

−0.14 (− 0.29, 0.01)

−0.03 (− 0.15, 0.09)

−0.05 (− 0.14, 0.04)

0.02 (− 0.07, 0.11)

−0.02 (− 0.12, 0.08)

Interaction

 Previous testing occasions X peri-menopause

−0.01 (− 0.12, 0.09)

0.05 (− 0.05, 0.15)

0.07 (− 0.01, 0.15)

0.06 (− 0.00, 0.12)

0.00 (− 0.05, 0.06)

−0.01 (− 0.08, 0.05)

 Previous testing occasions X post-menopause

0.09 (− 0.00, 0.18)

0.09 (0.01, 0.18)

0.05 (− 0.02, 0.12)

−0.03 (− 0.08, 0.02)

0.02 (− 0.02, 0.07)

0.04 (− 0.02, 0.09)

  1. Analyses are conducted in the main analysis participants, with adjusted for number of previous testing occasions (practice effects), menopausal stage, fieldworker effects, age (centred at 56), education (baseline CSE/vocational/O-level) and age at first pregnancy (centred at 26)