Fig. 2From: Novel compound heterozygous mutation in WEE2 is associated with fertilization failure: case report of an infertile woman and literature reviewConservation analysis and location, of WEE mutations. a Mutation p. Leu316Phe was conserved among different species. b Position of mutation c.946C > T (p. Leu316Phe) and c.1535 + 3A > G in the genome and protein structure. The red region represents the nuclear export sequence (NES)Back to article page