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Table 2 Baseline disease characteristics and healthcare histories

From: Real-world characteristics of women with endometriosis-related pain entering a multidisciplinary endometriosis program

Parameter

Single-provider cohort entering the CERT clinic (n = 638)

Type of pain, n (%)a

 

 Dysmenorrhea

511 (80)

 Dyspareunia

369 (58)

 NMPP

498 (78)

Additional symptoms, n (%)

 

 Pelvic tenderness

275 (43)

 Abdominal tenderness

140 (22)

 Hematuria

12 (2)

 Rectal bleeding

38 (6)

Comorbidity identified by transvaginal ultrasound

 

 Uterine fibroids (> 3 cm)

 

  No

572 (90)

  Yes

66 (10)

 Suspected adenomyosis

 

  No

593 (93)

  Yes

45 (7)

 Suspected endometrioma (> 2 cm)

 

  No

530 (83)

  Yes

108 (17)

 Other ovarian cysts (> 2 cm)

 

  No

565 (89)

  Yes

73 (11)

Years since onset of pelvic pain to endometriosis surgical diagnosis

 

 n

285

 Mean (SD)

6.3 (6.8)

 Range

0–32

Years from surgical diagnosis of endometriosis to entry into the CERT clinic

 

 n

392

 Mean (SD)

6.9 (6.9)

 Range

0.02–35.2

Years from onset of pelvic pain to entry into the CERT clinic

 

 n

527

 Mean (SD)

10.1 (9.0)

 Range

0–40.1

Duration of pain, n (%)

 

 < 5 years

215 (41)

 5–10 years

83 (16)

 > 10 years

229 (44)

Years since diagnosis, n (%)

 

 < 1 year

77 (20)

 1–5 years

122 (31)

 5–10 years

90 (23)

 > 10 years

103 (27)

Prior surgical procedures to treat endometriosisb, n (%)

670 (100)

 Hysterectomy

42 (6)

 Left oophorectomy

35 (5)

 Right oophorectomy

16 (2)

 Bilateral oophorectomy

5 (1)

 Unilateral cystectomy

76 (11)

 Bilateral cystectomy

16 (2)

 Conservative surgery

480 (72)

Analgesic use, n (%)

 

 NSAIDs

 

  Current

219 (34)

  Prior

86 (14)

 Opioids

 

  Current

158 (25)

  Prior

108 (17)

Combination NSAID/opioidc

 

 Current

84 (13)

Endometriosis medication use, n (%)

 

 Oral contraceptives

 

  Current

177 (28)

  Prior

391 (63)d

 GnRH agonist (Lupron)

 

  Current

26 (4)

  Prior

120 (19)

 Depo provera

 

  Current

17 (3)

  Prior

80 (13)

 Oral progestin

 

  Current

36 (6)

  Prior

40 (6)

 Danazol

 

  Current

1 (0.2)

  Prior

4 (1)

 IUD

 

  Current

20 (3)

  Prior

54 (9)

 Aromatase inhibitors

 

  Current

5 (1)

  Prior

7 (1)

Gabapentin

 

 Current

18 (3)

 Prior

8 (1)

 Antidepressant

 

  Current

125 (20)

  Prior

39 (6)

Previous healthcare providers, n

638

  Mean (SD)

4.0 (3.7)

 Range

0–26

  1. Percentages reflect the number of patients with non-missing data. Numbers may not add up to 638 because of missing data
  2. aThe number (%) of patients reporting mild, moderate, or severe pain for each condition. Total number as follows: dysmenorrhea, n = 569; NMPP, n = 571; dyspareunia, n = 551
  3. bData based on the five most recent surgeries. Women described here may have had more than one surgery and so more than one procedure
  4. cPrior use of NSAIDS and opioids at the same time could not be confirmed accurately
  5. dPrior oral contraceptive use includes a very few women who used etonogestrel/ethinyl estradiol vaginal ring
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