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Table 3 Biberoglu and Behrman pain assessment stratified by select patient characteristics

From: Real-world characteristics of women with endometriosis-related pain entering a multidisciplinary endometriosis program

Parameter, mean (SD)   Dysmenorrhea   NMPP   Dyspareunia   Total pelvic pain score
(n = 506)
Overall   2.14 (1.00)   1.76 (0.98)   1.31 (1.14)   5.22 (2.16)
Age n   n   n   n  
 < 30 200 2.32 (0.91) 193 1.94 (0.88) 183 1.44 (1.05) 172 5.71 (1.86)
 30–39 234 2.15 (0.95) 234 1.67 (0.99) 228 1.31 (1.13) 210 5.16 (2.16)
 ≥ 40 135 1.84 (1.13) 144 1.65 (1.06) 140 1.14 (1.25) 124 4.62 (2.38)
 p value    < 0.001   0.005   0.06    < 0.001
 F value   9.53   5.35   2.89   9.57
 df   2, 566   2, 568   2, 548   2, 503
Number of previous providers n   n   n   n  
 0–1 60 1.93 (0.86) 61 1.62 (0.95) 59 1.07 (1.07) 57 4.58 (2.00)
 2 57 2.25 (0.91) 58 1.66 (0.91) 5758 1.11 (1.08) 54 4.94 (1.93)
 3 57 2.09 (0.98) 60 1.83 (0.91) 77 1.41 (1.18) 55 5.38 (2.08)
 4–5 77 1.97 (1.11) 83 1.72 (0.99) 56 1.42 (1.16) 72 5.14 (2.31)
 ≥ 6 59 2.20 (1.11) 61 2.11 (0.90)   1.43 (1.16) 54 5.74 (1.95)
 p value   0.34   0.03a   0.18   0.04a
 F value   1.13   2.76   1.56   2.48
 df   4, 305   4, 318   4, 302   4, 287
Duration of pain n   n   n   n  
  < 5 193 2.03 (1.00) 190 1.69 (1.00) 182 1.26 (1.12) 166 4.98 (2.21)
 5–10 75 2.40 (0.87) 74 1.88 (0.94) 67 1.45 (1.18) 63 5.67 (1.82)
 > 10 206 2.23 (0.95) 211 1.79 (0.96) 205 1.37 (1.14) 191 5.37 (2.04)
 p value   0.01   0.35   0.44   0.05
 F value   4.57   1.06   0.82   2.97
 df   2, 471   2, 472   2, 451   2, 417
Years since diagnosis n   n   n   n  
 < 1 69 2.14 (1.06) 65 1.75 (1.00) 61 1.18 (1.16) 57 5.00 (2.29)
 1–5 108 2.20 (1.00) 110 1.92 (0.95) 105 1.48 (1.16) 94 5.76 (2.11)
 5–10 76 2.00 (1.14) 81 1.96 (1.03) 74 1.35 (1.17) 68 5.38 (2.34)
 > 10 88 2.03 (1.08) 95 1.76 (0.95) 95 1.41 (1.22) 83 5.17 (2.26)
 p value   0.54   0.38   0.47   0.17
 F value   0.72   1.02   0.85   1.67
 df   3, 337   3, 347   3, 331   3, 298
Current medications n   n   n   n  
 Opioids         
  No 425 2.01 (1.00) 423 1.56 (0.93) 410 1.23 (1.13) 378 4.80 (2.13)
  Yes 144 2.51 (0.86) 148 2.32 (0.90) 141 1.54 (1.14) 128 6.43 (1.74)
  p value    < 0.001    < 0.001   0.006    < 0.001
  F value   28.75   73.57   7.70   60.55
  df   1, 567   1, 569   1, 549   1, 504
 NSAIDS         
  No 373 2.05 (1.05) 379 1.68 (0.98) 358 1.28 (1.12) 335 5.03 (2.18)
  Yes 196 2.31 (0.86) 192 1.91 (0.96) 193 1.36 (1.17) 171 5.58 (2.09)
  p value   0.004    < 0.001   0.48   0.006
  F value   8.57   6.80   0.51   7.66
  df   1, 567   1, 569   1, 559   1, 504
Ultrasound findings n   n   n   n  
 Fibroids         
  No 511 2.16 (0.98) 517 1.77 (0.96) 497 1.33 (1.14) 459 5.27 (2.12)
  Yes 58 1.95 (1.10) 54 1.67 (1.15) 54 1.13 (1.12) 47 4.70 (2.51)
  p value   0.12   0.48   0.22   0.09
  F value   2.38   0.50   1.50   2.94
  df   1, 567   1, 569   1, 549   1, 504
 Ovarian cysts         
  No 506 2.13 (1.01) 503 1.78 (0.98) 490 1.32 (1.15) 448 5.24 (2.19)
  Yes 63 2.19 (8.77) 68 1.59 (1.01) 61 1.21 (1.04) 58 5.00 (1.96)
  p value   0.66   0.13   0.48   0.42
  F value   0.19   2.28   0.50   0.65
  df   1, 567   1, 569   1, 549   1, 504
 Endometrioma         
  No 470 2.14 (1.00) 475 1.81 (0.97) 454 1.34 (1.15) 417 5.31 (2.13)
  Yes 99 2.11 (0.95) 96 1.47 (0.97) 97 1.16 (1.10) 89 4.75 (2.33)
  p value   0.76   0.002   0.17   0.03
  F value   0.09   10.08   1.91   4.99
  df   1, 567   1, 569   1, 549   1, 504
 Adenomyosis         
  No 528 2.14 (1.00) 532 1.76 (0.98) 511 1.30 (1.14) 468 5.21 (2.15)
  Yes 41 2.17 (1.00) 39 1.77 (1.01) 40 1.43 (1.15) 38 5.34 (2.27)
  p value   0.83   0.93   0.51   0.71
  F value   0.05   0.01   0.44   0.14
  df   1, 567   1, 569   1, 549   1, 504
  1. Pain assessment scores for dysmenorrhea, dyspareunia, and NMPP range from 0–3. Total pelvic pain score ranges from 0–9. Analyses include patients reporting no pain, mild pain, moderate pain, or severe pain for each condition. p values were obtained from the overall analysis of variance
  2. aOverall analysis of variance was not significant. Significant differences between the 0–1 and six or more categories were demonstrated by appropriate post hoc comparison tests