Table 1 Demographic details of study cohorts
From: Pelvic organ prolapse and uterine preservation: a cohort study (POP-UP study)
Variable | Total population N = 294 | Uterine sparing (LSH) N = 43 | Concomitant Hysterectomy (LSCH + LSC & TLH + LSC) N = 251 | p | |
|---|---|---|---|---|---|
BMI [Median (range)] | 26.4 (17.7–37.2) | 25.2 (17.7–31.6) | 26.6 (19.2–37.2) | 0.006a | |
Age [Median (range)] | 63.0 (28–84) | 49.0 (28–70) | 64.0 (37–84) | < 0.0001a | |
Parity [Median (range)] | 2.0 (0–9) | 2.0 (1–5) | 2.0 (0–9) | 0.063a | |
Cardiovascular disease [N (%)] | 149 (50.7%) | 9 (20.9%) | 140 (55.8%) | < 0.0001b | |
Diabetes mellitus [N (%)] | 40 (13.6%) | 1 (2.3%) | 39 (15.5%) | 0.020b | |
Previous DVT or pulmonary embolism [N (%)] | 39 (13.3%) | 3 (7.0%) | 36 (14.3%) | 0.188b | |
Asthma [N (%)] | 22 (7.5%) | 1 (2.3%) | 21 (8.4%) | 0.219c | |
Previous abdominal surgical history [N (%)] | 137 (46.6%) | 17 (39.5%) | 120 (47.8%) | 0.315b | |
Previous gynecologic surgery [N (%)] | 90 (30.6%) | 15 (34.9%) | 85 (33.9%) | 0.896b | |
Previous POP surgery [N (%)] | 6 (2.0%) | 2 (4.7%) | 4 (1.6%) | 0.214c | |
Point C | POP Q stage I | 19 (6.5%) | 5 (11.6%) | 14 (5.6%) | 0.073b |
POP Q stage II | 159 (54.1%) | 24 (55.8%) | 135 (53.8%) | ||
POP Q stage III | 78 (26.5%) | 11 (25.6%) | 67 (26.7%) | ||
POP Q stage IV | 38 (12.9%) | 3 (7.0%) | 55 (21.9%) | ||
Point Ba | POP Q stage I | 3 (1.0%) | 1 (2.3%) | 2 (0.8%) | < 0.0001b |
POP Q stage II | 65 (22.1%) | 28 (65.1%) | 37 (14.7%) | ||
POP Q stage III | 165 (56.1%) | 11 (25.6%) | 154 (61.4%) | ||
POP Q stage IV | 51 (17.4%) | 3 (7.0%) | 48 (19.1%) | ||
Point Bp | POP Q stage I | 96 (32.7%) | 13 (30.2%) | 83 (33.1%) | 0.634b |
POP Q stage II | 132 (44.9%) | 22 (51.2%) | 110 (43.8%) | ||
POP Q stage III | 46 (15.6%) | 7 (16.3%) | 39 (15.5%) | ||
POP Q stage IV | 20 (6.8%) | 1 (2.3%) | 19 (7.6%) | ||
Stress urinary incontinence [N (%)] | 87 (29.6%) | 11 (25.6%) | 76 (60.3%) | 0.533b | |
Urge urinary incontinence [N (%)] | 66 (22.4%) | 8 (18.6%) | 58 (23.1%) | 0.513b | |
Hesitancy: a delay in initiating micturition [N (%)] | 136 (46.3%) | 13 (30.2%) | 123 (49.0%) | 0.023b | |
Urinary retention [N (%)] | 126 (42.9%) | 21 (48.8%) | 115 (45.8%) | 0.714b | |
Constipation [N (%)] | 62 (21.1%) | 4 (9.3%) | 58 (23.1%) | 0.040b | |
Anal incontinence [N (%)] | 102/266 (38.3%) | 16/41 (39.0%) | 86/225 (38.2%) | 0.923b | |
Pre-op UDI [median (range)] | 51.2 (0–189) | 52.6 (5.8–164) | 51.2 (0–189) | 0.481a | |
Pre-op POPDI [median (range)] | 68.5 (0–282) | 58.9 (10.7–152) | 69.6 (0–282) | 0.204a | |
Pre-op CRADI [median (range)] | 35.1 (0–216) | 34.2 (0–164) | 36.4 (0–216) | 0.963a | |
Pre-op PFDI [median (range)] | 171.7 (0–600) | 148.0 (16.5–442) | 1712.4 (0–600) | 0.524a | |