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Table 4 Effect of BMI in subjects with, and without, PCOS: Metabolic parameters

From: Effect of body mass index (BMI) on phenotypic features of polycystic ovary syndrome (PCOS) in Singapore women: a prospective cross-sectional study

Variables Patient category BMI Mean ± SD Model A Model B Model C
Fold change Adjusted difference (95% CI) Fold change Adjusted difference (95% CI) Fold change Adjusted difference (95% CI)
HOMA-IR Healthy Normal 1.29 ± 0.15 1.0 Ref     
High 2.20 ± 0.19 1.71 0.68 (0.01, 1.35)* 1.0 Ref   
PCOS Normal 1.23 ± 0.24 0.95 0.05 (− 0.74, 0.84) 0.56 − 0.63 (− 1.53, 0.27) 1.0 Ref
High 3.53 ± 0.22 2.74 1.48 (0.71. 2.25)*** 1.60 0.80 (− 0.03, 1.64) 2.87 1.43 (0.48, 2.38)***
Cholesterol (mmol/L) Healthy Normal 4.63 ± 0.07 1.0 Ref     
High 5.10 ± 0.08 1.10 0.42 (0.09, 0.74)** 1.0 Ref   
PCOS Normal 4.71 ± 0.11 1.02 0.09 (− 0.30, 0.48) 0.92 − 0.33 (− 0.77, 0.11) 1.0 Ref
High 4.96 ± 0.10 1.07 0.16 (− 0.21, 0.54) 0.97 − 0.25 (− 0.66, 0.16) 1.05 0.08 (− 0.39, 0.54)
Triglycerides (mmol/L) Healthy Normal 0.80 ± 0.06 1.0 Ref     
High 1.30 ± 0.07 1.63 0.35 (0.15, 0.55)*** 1.0 Ref   
PCOS Normal 0.81 ± 0.09 1.01 0.03 (− 0.21, 0.27) 0.62 − 0.32 (− 0.59, − 0.05)* 1.0 Ref
High 1.24 ± 0.08 1.55 0.36 (0.13, 0.59)*** 0.95 0.01 (− 0.24, 0.26) 1.53 0.33 (0.04, 0.61)*
HDL (mmol/L) Healthy Normal 1.59 ± 0.03 1.0 Ref     
High 1.35 ± 0.03 0.85 − 0.21 (− 0.36, − 0.07)*** 1.0 Ref   
PCOS Normal 1.63 ± 0.04 1.03 0.00 (− 0.17, 0.17) 1.21 0.21 (0.01, 0.40)* 1.0 Ref
High 1.28 ± 0.04 0.81 − 0.33 (− 0.50, − 0.17)*** 0.95 − 0.12 (− 0.30, 0.06) 0.74 − 0.33 (− 0.53, − 0.12)***
LDL (mmol/L) Healthy Normal 2.66 ± 0.06 1.0 Ref     
High 3.20 ± 0.08 1.20 0.45 (0.17, 0.74)*** 1.0 Ref   
PCOS Normal 2.72 ± 0.10 1.02 0.15 (− 0.19, 0.49) 0.85 − 0.30 (− 0.69, 0.08) 1.0 Ref
High 3.12 ± 0.09 1.18 0.37 (0.04, 0.70)* 0.98 − 0.08 (− 0.44, 0.27) 1.15 0.22 (− 0.19, 0.62)
  1. HOMA‐IR, homoeostatic model assessment‐insulin resistance; HDL, high-density lipoprotein; LDL, low-density lipoprotein