Table 3 Univariate and multivariate analysis of risk factors for residual lesions in women with positive margins
Variable | Residual rate (%) | Univariate | Multivariate | |
|---|---|---|---|---|
P value | OR (95%CI) | P value | ||
Age(years) | ||||
≤ 35 | 24.39 (20/82) | 0.026 | 1.429 (1.056–2.968) | 0.037 |
> 35 | 38.65 (63/163) | |||
Gravidity | ||||
≤ 3 | 33.70(31/92) | 0.507 | Variable removed | |
> 3 | 33.99(52/153) | |||
Parity | ||||
≤ 2 | 30.30(40/132) | 0.428 | Variable removed | |
> 2 | 38.05(43/113) | |||
Cytology | ||||
Minor abnormalities | 15.19(12/79) | < 0.001 | 3.143 (1.986–5.113) | < 0.001 |
Major abnormalities | 42.77(71/166) | |||
High-risk HPV | ||||
Yes | 44.59(33/74) | 0.020 | 1.483 (1.345–3.226) | 0.029 |
No | 29.24(50/171) | |||
Transformation zone | ||||
I and II | 25.32(39/154) | < 0.001 | 2.996 (1.636–4.825) | 0.001 |
III | 48.35(44/91) | |||
ECC | ||||
Positive | 45.88(39/85) | 0.005 | 2.127 (1.118–2.970) | 0.007 |
Negative | 27.50(44/160) | |||
Quadrant involvement | ||||
Single | 25.19(33/131) | 0.003 | 1.824 (1.441–2.609) | 0.004 |
Multiple | 43.86(50/114) | |||
Glandular involvement | ||||
No | 32.82(43/131) | 0.636 | Variable removed | |
Yes | 35.09(40/114) | |||
CIN grade | ||||
CIN2 | 30.19(32/106) | 0.251 | Variable removed | |
CIN3 | 36.69(51/139) | |||
Site of margin involvement | ||||
Endo | 33.33(25/75) | 0.866 | Variable removed | |
Ecto | 32.35(33/102) | |||
Endo/Ecto | 36.76(25/68) | |||
Method of secondary operation | ||||
CKC | 29.27(24/82) | 0.349 | Variable removed | |
Total hysterectomy | 38.70(36/93) | |||
LEEP | 32.86(23/70) | |||