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Table 1 Clinicopathological features of 42 patients with recurrence of hormone receptor-positive/HER2 negative breast cancer not receiving chemotherapy

From: Prediction of distant metastatic recurrence by tumor-infiltrating lymphocytes in hormone receptor-positive breast cancer

Parameters

Number of all patients (n = 42) (%)

Age at operation (years old)

Median 59 (range 37–79)

Tumor size (mm)

Median 20.5 (range 9.5–49.3)

Pathological lymph node metastasis

pN0/pN1mi/pN1a

32 (76.2%)/3 (7.1%)/7 (16.7%)

Estrogen receptor

Negative/positive

1 (2.4%)/41 (97.6%)

Progesterone receptor

Negative/positive

3 (7.1%)/39 (92.9%)

Ki67

 ≤ 20%/ > 20%

35 (83.3%)/7 (16.7%)

Surgical treatment

Breast conserving treatment and adjuvant radiation therapy/mastectomy

18 (42.9%)/24 (57.1%)

Lymphatic invasion

ly0/ly1

21 (50.0%)/21 (50.0%)

Venous invasion

v0/v1

39 (92.9%)/3 (7.1%)

Nuclear grade

1/2/3

20 (47.6%)/16 (38.1%)/6 (14.3%)

Adjuvant endocrine therapy

TAM/TAM + LH-RH agonist/ANA

10 (23.8%)/7 (16.7%)/25 (59.5%)

Disease free survival (days)

1462 (132–3300)

Primary recurrence site

Local/regional lymph node/lung/bone/liver/bone + liver

18 (42.9%)/13 (30.9%)/7 (16.6%)/1 (2.4%)/1 (2.4%)/2 (4.8%)

TILs density

Absent/ ≤ 10%/ > 10%

6 (14.3%)/30 (71.4%)/6 (14.3%)

  1. HER2 human epidermal growth factor receptor 2, TAM tamoxifen, LH-RH luteinizing hormone-releasing hormone, ANA anastrozole, TILs tumor-infiltrating lymphocytes