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Table 1 Changes in serum markers in patients with different treatment time to remission

From: Significance of serum and pathological biomarkers in fertility-sparing treatment for endometrial cancer or atypical hyperplasia: a retrospective cohort study

 

Remission time

 < 6 months (n = 19)

Remission time

 ≥ 6 months (n = 31)

p-value

T0-Estradiol, pg/mL

105.2 ± 187.2

53.1 ± 83.9

0.322

T0-FSH, IU/L

5.5 ± 2.3

5.3 ± 3.1

0.831

T0-LH, IU/L

3.0 ± 2.1

3.8 ± 3.2

0.494

T0-T, nmol/L

1.0 ± 0.6

0.9 ± 0.7

0.672

T0-PRL, ng/mL

20.3 ± 11.2

21.0 ± 9.6

0.437

T0-HOMA-IR

2.2 ± 1.3

4.2 ± 2.0

0.004

T1-HOMA-IR

2.4 ± 1.5

3.6 ± 3.7

0.311

T2-HOMA-IR

2.7 ± 1.8

4.0 ± 2.9

0.185

T1 vs. T0-HOMA-IR

− 12%

− 39%

0.049

T2 vs. T0-HOMA-IR

25%

− 44%

0.020

T0-HbA1c, %

5.7 ± 0.4

5.6 ± 0.4

0.922

T0-FT4, pmol/L

16.4 ± 2.8

16.8 ± 1.9

0.688

T0-TSH, uIU/mL

2.1 ± 1.7

2.2 ± 0.9

0.864

  1. Bold part represents p-value less than or near 0.05
  2. E, estradiol; FSH, follicle-stimulating hormone; LH, luteinizing hormone; T, testosterone; PRL, prolactin; HOMA-IR, homeostasis model assessment of insulin resistance; HbA1c, glycosylated hemoglobin A1c; FT4, free thyroxine; TSH, thyroid-stimulating hormone