Table 4 Accuracy of colposcopic major changes in predicting high-grade lesion
From: Clinical application of the 2011 IFCPC colposcope terminology
Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | Youden index | |
|---|---|---|---|---|---|
Dense aceto-white epithelium | 73.2% (69.2–76.9%) | 87.9% (86.0–89.6%) | 70.4% (66.4–74.1%) | 89.3% (87.5–90.9%) | 0.611 |
Coarse mosaic | 17.0% (14.0–20.4%) | 97.6% (96.6–98.3%) | 73.3% (64.8–80.5%) | 74.9% (72.8–76.9%) | 0.145 |
Coarse punctation | 28.5% (24.8–32.6%) | 94.9% (93.6–96.0%) | 68.8% (62.4–74.7%) | 77.1% (75.0–79.1%) | 0.234 |
Sharp border | 4.8% (3.3–7.0%) | 99.1% (98.0–99.5%) | 67.6% (51.4–80.5%) | 72.6% (70.5–74.6%) | 0.039 |
Inner border sign | 2.1% (1.1–3.8%) | 99.9% (99.4–100.0%) | 84.6% (56.5–96.9%) | 72.2% (70.1–74.2%) | 0.020 |
Ridge sign | 2.3% (1.3–4.0%) | 99.8% (99.3–100.0%) | 80.0% (54.1–93.7%) | 72.2% (70.1–74.2%) | 0.021 |
Cuffed crypt openings | 35.45% (31.5–39.7%) | 91.1% (89.5–92.6%) | 61.1% (55.5–66.5%) | 78.2% (76.1–80.2%) | 0.266 |