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Table 5 Accuracy of colposcopic Lugol’s staining negativity in predicting normal or benign, low-grade lesion, high-grade lesion and carcinoma

From: Clinical application of the 2011 IFCPC colposcope terminology

 

Sensitivity

(95% CI)

Specificity

(95% CI)

Positive predictive value

(95% CI)

Negative predictive value

(95% CI)

Youden index

Normal or benign

81.3%

(77.9–84.3%)

1.5%

(1.0–2.4%)

27.7%

(25.7–29.9%)

14.8%

(9.6–22.1%)

− 0.172

LSIL

98.0%

(96.5–98.8%)

9.6%

(8.1–11.4%)

36.7%

(34.4–39.0%)

89.8%

(83.3–94.1%)

0.076

HSIL

99.0%

(97.7–99.6%)

9.3%

(7.9–11.0%)

30.1%

(27.9–32.3%)

96.1%

(90.9–98.6%)

0.084

Carcinoma

99.0%

(93.8–100.0%)

7.3%

(6.2–8.6%)

5.6%

(4.6–6.8%)

99.2%

(95.3–100.0%)

0.062

  1. LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial