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Table 1 Overview of quantitative measures and measurement instruments in the OPTIMUM-study

From: Towards OPtimal TIming and Method for promoting sUstained adherence to lifestyle and body weight recommendations in postMenopausal breast cancer survivors (the OPTIMUM-study): protocol for a longitudinal mixed-method study

Variables

Instrument

Wave

1a

Wave 2a

Wave 3a

Objective

Sociodemographic and health-related variables

     

 Demographics (education, marital status, employment status)

Demographic questions

x

x

x

1b

 Comorbidities

Self-administered Comorbidity Questionnaire (SCQ) [60]

x

x

x

1b

 Estrogen/breast cancer related variables

Questionnaire items concerning age of onset menarche in years, number of pregnancies, total duration of breastfeeding, age of onset menopause in years

x

  

1b

 Cancer-specific health related quality of life

European Organization for Research and Treatment Quality of Life Questionnaire (EORTC QLQ-C30) [61]

 

x

x

1a

Overweight and body fat distribution

     

 BMI

Weight in kg/(Height in m)2

x

x

x

1a, 2a

 Hip- and waist circumference

Self-administrated measurement by use of measurement tape

x

x

x

1a, 2a

Physical activity + sedentary behavior

     

 Physical activity level and sedentary behavior

Physical Activity Scale for the Elderly (PASE) [42]

x

x

x

1a, 2a

 Physical activity accelerometry

7-day accelerometer data (ActiGraph) [46]

Physical activity measures: Average acceleration (AvAcc), Intensity Gradient (IG), total minutes light, moderate and vigorous physical activity per day, total minutes of inactive time per day, most active continuous 30 min (M30) per day

 

x

x

1a, 2a

 Functional muscle strength

5Times-Sit-To-Stand functional muscle strength measurement: self-administrated measurement by use of stopwatch [50]

 

x

x

2b

Dietary intake

     

 Diet quality (including alcohol consumption)

Dutch Healthy Diet—index 15 (DHD-15), with minor adjustments [54]

x (shortened)

x

x

1a, 2a

 Dietary intake: energy and macronutrients

Online 3-day food diary: registration of all foods and drinks, in portion sizes of gram/ml, they have consumed during the day using the ‘Eetmeter’ from the Dutch ‘Voedingscentrum’

 

x

x

1a, 2a

Smoking

     

 Smoking behaviours

Smoking behaviour questions

x

x

x

1a, 2a

Sleep

     

 Sleep quality and disturbances

Pittsburgh Sleep Quality Index (PSQI) [55]

 

x

x

1a, 2a

 Sleep accelerometry

7-day accelerometer data (wristworn ActiGraph wGT3X) [46]

Sleep measures: sleep latency, sleep efficiency, daytime sleep, frequency of long sleep interruptions (> 5 min), total minutes of sleep per night

 

x

x

1a, 2a

Lifestyle and health related measures

     

 Readiness for lifestyle change

Assessed according to the transtheoretical model (not ready: pre-contemplation/contemplation); (ready: preparation/action/maintenance); (relapse: relapse) [29] with 1 item per recommendation

x

x

x

2a, 2b, 2c

 Need for support

Need for support assessed with 1 item per recommendation

x

x

x

1a, 2a, 2b, 2c

 Posttraumatic growth

Posttraumatic Growth Inventory (PGI) [62]

 

x

x

2b, 2c

 Self-compassion

Short Form Self-Compassion Scale [63]: 6 positive items only

x

x

x

2b, 2c

 Emotion regulation

Cognitive Emotion Regulation Questionnaire (CERQ)—short [64]

 

x

x

2b, 2c

 Mental and physical fatigue

Multidimensional Fatigue Inventory (MFI) [65]

 

x

x

2b, 2c

 Symptoms of depression and anxiety

Hospital anxiety and depression scale (HADS) [66]

 

x

x

2b, 2c

Biological determinants of cancer prognosis

     

 Inflammation

Pro- and anti-inflammatory cytokines (TNFα, IL-6, IL-10, IL-1Ra) and CRP

 

x

x

1c

 Metabolism

leptin, insulin, insulin growth factor-1, glucose, HbA1C, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, Vitamin D

 

x

x

1c

  1. awave 1 = 4–6 months after diagnosis; wave 2 = 1 year after diagnosis; wave 3 = 1.5 years after diagnosis