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Table 2 Comparison of serum bone turnover markers between baseline and 12 weeks after hysterectomy with bilateral oophorectomy

From: Effects of early estradiol valerate administration on bone turnover markers in surgically induced menopausal women

Bone turnover markers

Hormone treatment group (n = 21)

No treatment group (n = 20)

At baseline

At 12 weeks

p-value

At baseline

At 12 weeks

p-value

CTX; ng/ml

0.21 (0.17–0.35)

0.21 (0.14–0.34)

0.660

0.24 (0.19–0.34)

0.47 (0.28–0.65)

 < 0.001

P1NP; ng/ml

37.97 (26.09–54.62)

42.41 (31.42–63.61)

0.120

42.11 (35.26–72.57)

63.63 (54.98–80.45)

0.002

  1. Data was presented as median (IQR) and analyzed with Wilcoxon signed rank test