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Table 2 Correlation between the number of biopsies and the diagnosis of CIN2+ for all women, women without any visible changes of the cervix and women who underwent LEEP

From: Can biopsies be omitted after normal colposcopy in women referred with low-grade cervical cytology? A prospective cohort study

Diagnosis

Biopsy 1

Biopsy 1 + 2

Biopsy 1 + 2 + 3

Biopsy 1 + 2 + 3 + 4

n

% (95%CI)

n

% (95%CI)

n

% (95%CI)

n

% (95%CI)

All included women (n = 173)

No dysplasia

121

69.9 (62.5–76.7)

102

59.0 (51.2–66.4)

91

52.6 (44.9–60.2)

76

43.9 (36.4–51.7)

CIN1

33

19.1 (13.5–25.7)

44

25.4 (19.1–32.6)

52

30.1 (23.3–37.5)

59

34.1 (27.1–41.7)

CIN2+

19

11.0 (6.7–16.6)

27

15.6 (10.5–21.9)

30

17.3 (12.0–23.8)

38

22.0 (16.0–28.9)

Women without any visible changes of the cervix (n = 137)

No dysplasia

100

73.0 (64.7–80.2)

85

62.0 (53.4–70.2)

76

55.5 (46.7–64.0)

65

47.4 (38.9–56.1)

CIN1

27

19.7 (13.4–27.4)

37

27.0 (19.8–35.3)

45

32.8 (25.1–41.4)

50

36.5 (28.4–45.1)

CIN2+

10

7.3 (3.6–13.0)

15

10.9 (6.3–17.4)

16

11.7 (6.8–18.3)

22

16.1 (10.3–23.3)

Women who underwent LEEP (n = 21)

No dysplasia

5

23.8 (8.2–47.2)

3

14.3 (3.0–36.3)

3

14.3 (3.0–36.3)

0

0.0 (0–16.1)

CIN1

6

28.6 (11.3–52.2)

4

19.0 (5.4–41.9)

3

14.3 (3.0–36.3)

3

14.3 (3.0–36.3)

CIN2+

10

47.6 (25.7–70.2)

14

66.7 (43.0–85.4)

15

71.4 (47.8–88.7)

18

85.7 (63.7–97.0)

  1. CIN1, Cervical intraepithelial neoplasia grade 1; CIN2+, cervical intraepithelial neoplasia grade 2 or worse; LEEP, loop electrosurgical excision procedure