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Table 1 Characteristics of study participants by mammographic breast density among women in Karachi, Pakistan (n = 477)

From: Factors associated with mammographic breast density among women in Karachi Pakistan

Variables

Category

Fatty/fibroglandular (n = 178)

Heterogeneously dense (n = 198)

Dense (n = 101)

p value*

n (%)

n (%)

n (%)

Age groups (years)

    

 < 0.001

 

 < 35

7 (3.9)

12 (6.1)

13 (12.9)

 
 

35–45

30 (16.9)

69 (34.8)

46 (45.5)

 
 

46–54

57 (32.0)

51 (25.8)

29 (28.7)

 
 

55 and above

84 (47.2)

66 (33.3)

13 (12.9)

 

Education

    

0.023

 

 < Grade8

33 (18.6)

31 (15.7)

13 (12.9)

 
 

Grades 8–12

65 (36.7)

54 (27.4)

24 (23.8)

 
 

 > Grade12

79 (44.6)

112 (56.9)

64 (63.4)

 

Socioeconomic Status SES

    

0.866

 

Upper

43 (25.6)

48 (25.3)

20 (20.0)

 
 

Middle

114 (67.9)

129 (67.9)

73 (73.0)

 
 

Lower

11 (6.5)

13 (6.8)

7 (7.0)

 

Parity

    

0.004

 

Nullipara

21 (12.5)

18 (9.5)

21 (21.0)

 
 

1–3

78 (46.4)

112 (58.9)

55 (55.0)

 
 

 > 3

69 (41.1)

60 (31.6)

24 (24.0)

 

Age of mother at first live birth (AFB)

    

0.060

 

 < 20 years

39 (25.8)

29 (16.2)

11 (13.9)

 
 

20–29 years

98 (64.9)

126 (70.4)

54 (68.4)

 
 

 > 30 years

14 (9.3)

24 (13.4)

14 (17.7)

 

Breastfeeding duration

    

0.910

 

 < 12 months

26 (19.3)

35 (21.2)

15 (19.7)

 
 

 > 12 months

109 (80.7)

130 (78.8)

61 (80.3)

 

Age at menarche (years)

    

0.487

 

 < 12 years

26 (16.3)

22 (12.2)

12 (12.6)

 
 

12–13 years

95 (59.4)

105 (58.0)

51 (53.7)

 
 

 > 14 years

39 (24.4)

54 (29.8)

32 (33.7)

 

History of any comorbid

    

0.01

 

Yes

102 (57.3)

95 (48.0)

39 (38.6)

 
 

No

76 (42.7)

103 (52.0)

62 (61.4)

 

History of benign breast disease

    

0.001

 

Yes

33 (19.9)

61 (32.6)

46 (46.5)

 
 

No

133 (80.1)

126 (67.4)

53 (53.5)

 

Family history of breast cancer

    

 < 0–001

 

Yes

48 (28.6)

77 (40.7)

32 (32.0)

 
 

No

120 (71.4)

112 (59.3)

68 (68.0)

 

Menopausal status

    

 < 0.001

 

Menopause

125 (74.4)

102 (54.3)

40 (40.4)

 
 

Premenopause

43 (25.6)

86 (45.7)

59 (59.6)

 

Serum vitamin D level (ng/ml)

    

0.761

 

 < 20

78 (57.4)

82 (54.7)

47 (54.7)

 
 

20–30

21 (15.4)

30 (20.0)

19 (22.1)

 
 

 > 30

37 (27.2)

38 (25.3)

20 (23.3)

 

Mean BMI (SD)

Menopausal women

30.4 (4.8)

28.4 (4.9)

25.4 (4.2)

 < 0.001

 

Premenopausal women

27.9 (5.0)

28.2 (4.7)

25.0 (3.8))

 < 0.001

  1. BI-RADS: Breast Imaging Reporting and Data System (fatty and scattered glandular dense = categories A and B, heterogeneously dense = C, dense = D); chi-square test*