Women with polycystic ovary syndrome (PCOS) have reduced melatonin concentrations in their follicles and have mild sleep disturbances

Table 2 IVF outcomes of the control and polycystic ovarian syndrome (PCOS) group

	Controls (n = 36)	PCOS (n = 35)	P value
No. of oocytes retrieved	13.00 (9.25–16.00)	19.00 (15.00–24.00)	< 0.001^***
Rate of MII oocytes	85.6% (74.8–92.5%)	92.8% (72.0–100.0%)	0.143
IVF fertilization rate	53.7% ± 3.92% (n = 27)	65.7% ± 4.1% (n = 30)	0.011^*
ICSI fertilization rate	71.1% ± 5.94% (n = 12)	59.1% ± 7.4% (n = 5)	0.255
Rate of top quality embryos on D3	87.0% (57.1–100.0%)	73.1% (47.1–87.5%)	0.042^*
Rate of top quality blastocysts on D5/6	75.0% (50.0–100.0%)	64.6% (46.0–82.5%)	0.185

IVF, in vitro fertilization; ICSI, Intracytoplasmic sperm injection; *p < 0.05; ***p < 0.001
Rate of MII oocytes was based on the number of MII oocytes/the number of oocytes retrieved × 100%
Rate of oocytes fertilized was based on the number of oocytes fertilized/ the number of oocytes retrieved × 100%
ICSI was performed in 3 cycles and the rate was separately calculated
Rate of top quality embryos on D3 was based on the number of top quality embryos on D3/ the number of oocytes normal fertilized (oocytes with two pronucleus) × 100%
Rate of top quality blastocysts on D5/D6 was based on the rate of top quality blastocysts/the number of blastocysts continued to be cultured on D3 × 100%

ISSN: 1472-6874