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Table 4 Risk of uterine fibroids based on BET1L rs2280543 genotypes and vegetarian status

From: Risk of uterine leiomyoma based on BET1L rs2280543 single nucleotide polymorphism and vegetarian diet

Variable

OR (95% CI)

p value

BET1L rs2280543 genotype and vegetarian diet (ref: CC and non-vegetarian)

 CC and vegetarian

1.32 (0.90–1.94)

0.157

 CT/TT and non-vegetarian

0.78 (0.57–1.07)

0.122

 CT/TT and vegetarian

0.37 (0.15–0.91)

0.030

Age (ref: 30–39 years)

  

 40–49

3.08 (2.22–4.26)

< 0.001

 50–59

4.58 (3.00–6.99)

< 0.001

Alcohol intake (ref: No)

  

 Yes

1.31 (0.64–2.69)

0.456

Cigarette smoking (ref: No)

  

 Yes

1.03 (0.59–1.79)

0.919

Exercise (ref: No)

  

 Yes

1.08 (0.83–1.41)

0.577

Coffee intake (ref: No)

  

 Yes

1.16 (0.90–1.50)

0.254

Tea intake (ref: No)

  

 Yes

0.92 (0.71–1.20)

0.550

Hypertension (ref: No)

  

 Yes

1.29 (0.87–1.93)

0.203

Diabetes (ref: No)

  

 Yes

1.23 (0.78–1.95)

0.364

Hormone use (ref: No)

  

 Yes

1.23 (0.82–1.86)

0.320

Herbal medicine use (ref: No)

  

 Yes

1.72 (1.23–2.40)

0.002

Family history of uterine fibroid (ref: No)

  

 Yes

1.87 (1.40–2.49)

< 0.001

Miscarriage/abortion (ref: No)

  

 Yes

1.42 (1.09–1.85)

0.009

Fat intake score (ref:0–35)

  

 36–40

0.88 (0.62–1.23)

0.450

 41–44

0.82 (0.57–1.17)

0.263

 45–60

0.66 (0.46–0.94)

0.021

BMI

1.00 (0.97–1.04)

0.880

Menarcheal age

0.90 (0.82–0.99)

0.026

Parity

0.97 (0.83–1.12)

0.639

  1. OR, odds ratio; ref, reference; BMI, body mass index; CI, confidence interval