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Table 1 Demographic characteristics of breast cancer patients

From: Molecular phenotypes and clinical characterization of familial hereditary breast cancer among half and full sisters

Variable

NHBC

HBC

Total

CHBC

NCHBC

CHBC + NCHBC

Patients, n

152

18

20

38

190

Ages, years

61.69 ± 14.34

49.06 ± 6.42

60.75 ± 9.95

55.21 ± 10.24

60.41 ± 13.85

Anatomical site

 Left

90 (59.21%)

11 (61.11%)

8 (40%)

19 (50%)

109 (57.37%)

 Right

62 (40.79%)

7 (38.89%)

12 (60%)

19 (50%)

81 (42.63%)

Pathologic types, n

 Invasive ductal carcinoma

116 (76.32%)

11 (61.11%)

15 (75%)

26 (68.42%)

142 (74.74%)

 Ductal carcinoma in situ

21 (13.82%)

6 (33.33%)

4 (20%)

10 (26.32%)

31 (16.32%)

 Mucinous carcinoma

8 (5.26%)

0

1 (5%)

1 (2.63%)

9 (4.74%)

 Intraductal papillary carcinoma

5 (3.29%)

1 (5.56%)

0

1 (2.63%)

6 (3.16%)

 Medullary carcinoma

2 (1.31%)

0

0

0

2 (1.04%)

Cell differentiation, n

 Grade I/high-level

11 (7.24%)

3 (16.66%)

1 (5%)

4 (10.53%)

15 (7.89%)

 Grade II/middle-level

89 (58.55%)

12 (66.67%)

9 (45%)

21 (55.26%)

110 (57.89%)

 Grade III/low-level

52 (34.21%)

3 (16.66%)

10 (50%)

13 (34.21%)

65 (34.22%)

Pathological stages

T0–3N0–3M0

T0–3N0–3M0

T0–3N0–3M0

  

Lymph node metastasis, n

 Positive

51 (33.55%)

10 (55.55%)

10 (50%)

20 (52.63%)

71 (37.37%)

 Negative

101 (66.45%)

8 (44.45%)

10 (50%)

18 (47.37%)

119 (62.63%)

  1. Continuous variables are presented as mean ± standard deviation, categorical variables are presented as numbers (percentages)
  2. HBC hereditary breast cancer, NHBC non-hereditary breast cancer, CHBC contemporaneous hereditary breast cancer, NCHBC non-contemporaneous hereditary breast cancer