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Table 2 Selected variables in the SEER database by multivariate Cox regression analysis (training cohort)

From: A novel nomogram for predicting cancer-specific survival in women with uterine sarcoma: a large population-based study

Variable Hazard ratio 95% CI p value
Age at diagnosis 1.0116 1.0061–1.0172 < 0.001***
Race
 White Reference   
 Black 1.1698 1.0225–1.3383 0.022*
 Other 0.8481 0.6698–1.0739 0.171
Marital status
 Married Reference   
 Single 1.2181 1.0436–1.4217 0.012*
 SDW 1.2965 1.1230–1.4969 < 0.001***
 Other 1.2816 0.9740–1.6863 0.076
Insurance record
 Yes Reference   
 No 1.4851 1.1367–1.9404 0.004**
Tumor size
 ≤ 50 mm Reference   
 > 50 mm 1.4861 1.2674–1.7425 < 0.001***
 Unknown 1.3345 1.0802–1.6487 0.007**
Pathological grade
 I Reference   
 II 1.3135 0.7662–2.2518 0.321
 III 7.3773 4.5441–11.9771 < 0.001***
 IV 7.0185 4.3528–11.3165 < 0.001***
Histological type
 Sarcoma Reference   
 Leiomyosarcoma 0.6550 0.4839–0.8866 0.006**
 Adenosarcoma 0.6288 0.3919–1.0089 0.054
 Stromal sarcoma 0.9274 0.6623–1.2984 0.661
 Carcinosarcoma 0.6099 0.4535–0.8202 0.001**
SEER stage
 Localized Reference   
 Regional 1.8809 1.3831–2.5580 < 0.001***
 Distant 2.5199 1.6708–3.8005 < 0.001***
AJCC stage
 I Reference   
 II 1.0136 0.7096–1.4478 0.941
 III 1.7459 1.2843–2.3735 < 0.001***
 IV 2.2275 1.4818–3.3484 < 0.001***
Surgery status
 Yes Reference   
 No/unknown 2.7559 2.2503–3.3751 < 0.001***
Radiotherapy status
 Yes Reference   
 No/unknown 1.3267 1.1567–1.5216 < 0.001***
Chemotherapy status
 Yes Reference   
 No/unknown 1.5355 1.3509–1.7453 < 0.001***
  1. SDW Separated, divorced, and widowed, SEER Surveillance, Epidemiology, and End Results, HR hazard ratio, AJCC American Joint Committee on cancer
  2. *p < 0.05, **p < 0.01, ***p < 0.001