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Table 3 Odds ratio for dense breast among premenopausal women. In the multivariate analysis, adjusted by age, BMI, and alcohol status, parity still showed a significant relationship. Compared with women with more than two parity, two parity, single parity, nulliparity showed a higher risk of dense breast (OR: 1.458 (95% CI; 1.123–1.894), OR: 2.349 (95% CI; 1.801–3.064), OR: 3.222 (95% CI; 2.500–4.151), respectively)

From: Impact of childbirth history on dense breast in mammographic screening: a cross-sectional study

 

Univariate

p

Multivariate

p

Age

0.941 (0.933–0.949)

 < 0.001

0.958 (0.949–0.967)

 < 0.001

BMI

0.756 (0.742–0.770)

 < 0.001

0.756 (0.742–0.771)

 < 0.001

Parity

 0

2.782 (2.206–3.508)

 < 0.001

3.222 (2.500–4.151)

 < 0.001

 1

2.229 (1.747–2.844)

 < 0.001

2.349 (1.801–3.064)

 < 0.001

 2

1.490 (1.170–1.896)

 < 0.001

1.458 (1.123–1.894)

0.005

 ≥ 3 (ref)

–

–

–

–

 Trend*

0.728 (0.693–0.764)

 < 0.001

0.676 (0.640–0.714)

 < 0.001

Smoking status

 Never (ref)

–

–

–

–

 Past

1.001 (0.877–1.142)

0.991

0.969 (0.862–1.115)

0.592

 Current

0.828 (0.670–1.022)

0.079

0.699 (0.549–0.889)

0.003

Alcohol status

 Non (ref)

–

–

–

–

 Occasional

1.091 (0.955–1.246)

0.199

1.000 (0.862–1.160)

0.998

 Regular

1.205 (1.091–1.330)

 < 0.001

1.097 (0.981–1.227)

0.106

Family history of breast cancer

1.006 (0.897–1.128)

0.921

–

–

Hormonal therapy

0.925 (0.813–1.053)

0.238

0.937 (0.812–1.082)

0.378

  1. *To calculate p for trend, variables were modeled as continuous value