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Table 2 Comparison of efficacy indicators (n%)

From: Efficacy evaluation of albumin-bound paclitaxel combined with carboplatin as neoadjuvant chemotherapy for primary epithelial ovarian cancer

Efficacy index

Nab-TC (n = 40)

TC (n = 40)

Statistics

P value

Number (percent)

    

Residual disease at IDS

  

χ2 = 0.287

0.592

 R1

30(75)

32(80)

  

 R0

10(25)

8(20)

  

 Postoperative blood transfusion

2(5)

14(35)

-

0.001

 Postoperative infusion of human albumin

10(25)

22(55)

χ2 = 7.500

0.006

Percentage drop of CA-125 value

    

 > 90%

26(65)

8(20)

χ2 = 16.573

0.000

 > 95%

14(35)

6(15)

χ2 = 4.267

0.039

 < 100U/mL

28(70)

12(30)

χ2 = 12.800

0.001

 ORR

18(45)

16(40)

χ2 = 0.205

0.651

Mean number ± SD

    

 Operation time (min)

135.75 ± 41.333

139.65 ± 46.853

t = 0.395

0.694

 Intraoperative blood loss (mL)

147.5 ± 120.336

208.0 ± 142.383

t = 2.053

0.043

 Postoperative hospital stay (day)

6.9 ± 1.780

8.9 ± 4.062

t = 2.852

0.006

QOL

    

 Functional areas score

36.88 ± 2.766

39.63 ± 2.404

t = 4.746

0.001

 Symptom areas score

32.03 ± 2.537

35.60 ± 3.209

t = 5.527

0.001

 General health areas score

8.25 ± 1.373

7.25 ± 1.171

t = −3.505

0.001

  1. R1: diameter of residual lesion < 1 cm, R0: no macroscopic residual tumor, ORR: objective remission rate, QOL: quality of life