Table 2 Factors Affecting Attendance at HGRRC among women diagnosed with a BRCA1/2 pathogenic variant in Nova Scotia, Canada between January 1, 2006 and December 31, 2016
Factor | Attended (n = 135) n (%) | Declined (n = 65) n (%) | p-value |
|---|---|---|---|
Age at time of genetic diagnosis, mean (SD) | 44 (13) | 46 (17) | 0.78 |
Personal history of breast cancer | 59 (44) | 32 (50) | 0.40 |
Personal history of ovarian cancer | 3 (2) | 1 (2) | 1.00 |
Family history of breast cancer | 126 (93) | 60 (94) | 0.91 |
Family history of ovarian cancer | 62 (46) | 21 (33) | 0.08 |
Risk-reducing surgery prior to HGRRC attendance | 0 (0) | 8 (13) | < 0.001* |
Hysterectomy for non-risk-reducing indication | 6 (4) | 12 (19) | 0.001* |
Tubal ligation for non-risk-reducing indication | 20 (15) | 4 (6) | 0.10 |
BSO for non-risk-reducing indication | 3 (2) | 8 (13) | 0.001* |
Risk-reducing bilateral mastectomy | 16 (12) | 2 (3) | 0.06 |