Table 1 Clinical characteristics of patients infected by Corynebacterium kroppenstedtii
Characteristic | N = 133 | NGLM (n = 75) | GLM (n = 57) | P |
|---|---|---|---|---|
(All were female patients) | (Exclude one lactation mastitis patients) | |||
Age in years, median (range) | 32 (11–56) | 31 (29–34) | 32 (29–35) | 0.43 |
Weight in kg, median (range) | 59.8 (43.0–88.0); n = 98 | 58.0 (52.5–64.5); n = 41 | 57.8 (53.0–66.0); n = 56 | 0.88 |
BMI in kg/m2, median (range) | 23.0 (16.8–32.4);n = 62 | 22.1 (20.3–25.0); n = 20 | 22.5 (20.9–24.9); n = 41 | 0.12 |
Low weight, < 18.5 | 1 (1.6%) | 0 (0.0%) | 1 (2.4%) | |
Normal weight, 18.5–24 | 40 (59.7%) | 10 (50.0%) | 30 (73.2%) | |
Obesity, ≥ 24 | 21 (38.7%) | 10 (50.0%) | 10 (24.4%) | |
Clinical presentation | ||||
Nonlobular granulomatous mastitis | 76 (57.1%) | |||
Lobular granulomatous mastitis | 57 (42.9%) | |||
Laterality | n = 133 | 0.74 | ||
Left | 63 (47.4%) | 33 (44.0%) | 29 (50.9%) | |
Right | 60 (45.1%) | 36 (48.0%) | 24 (42.1%) | |
Bilateral | 10 (7.5%) | 6 (8.0%) | 4 (7%) | |
Symptoms | ||||
Pain | 120 | 68 (89.5%) | 52 (91.2) | 0.74 |
Pus | 52 | 43 (56.0%) | 19 (33.3%) | 0.01* |
Mass | 131 | 74 (97.4%) | 57 (100.0%) | 0.61 |
Two or more of the above symptoms | 127 | 74 (94.9%) | 55 (96.5%) | 0.65 |
Laboratory test result, median (range) | ||||
WBC, × 109/L | 9.3 (4.1–18.7); n = 107 | 8.95 (6.81–11.05) | 8.95 (7.45–11.05) | 0.74 |
NEUT, × 109/L | 7.3 (2.0–78.4); n = 106 | 5.75 (4.39–8.16) | 6.40 (5.11–8.43) | 0.27 |
LYMPH, × 109/L | 2.03 (0.58–16.30); n = 106 | 1.85 (1.43–2.29) | 1.69 (1.38–2.17) | 0.45 |
CRP, mg/L | 15.9 (0.5–109.4); n = 66 | 6.05 (4.10–33.40) | 12.50 (1.50–10.30) | 0.03* |
Medical History | ||||
Hypertension | 1 | 0 | 1 | |
Mammary gland tumor | 3 | 1 | 2 | |
Depression | 1 | 0 | 1 | |
Childbirth history | n = 116 | 0.68 | ||
0 | 4 | 2 (3.3%) | 2 (3.6%) | |
1 | 71 | 34 (56.7%) | 37 (67.3%) | |
2 | 36 | 21 (35.0%) | 14 (25.5%) | |
3 | 5 | 3 (5.0%) | 2 (3.6%) | |
History of lactation in months, median (range) 10.5 (0–48); n = 110 | 0.15 | |||
< 12 | 70 | 33 (61.1%) | 37 (67.3%) | |
12–24 | 32 | 19 (35.2%) | 12 (21.8%) | |
> 24 | 8 | 2 (3.7%) | 6 (10.9%) | |
Clinical Treatment with Medications | n = 114 | < 0.01* | ||
Steroid | 22 | 9 (16.7%) | 13 (22.0%) | |
Antibiotic | 56 | 40 (74.1%) | 15 (25.4%) | |
Steroid and antibiotic | 36 | 5 (9.3%) | 31 (52.3%) | |
Invasive Clinical Treatment | n = 64 | 0.01* | ||
Punctures | 29 | 7 (38.9%) | 22 (48.9%) | |
Drainage | 13 | 8 (44.4%) | 5 (11.1%) | |
Punctures and drainage | 22 | 3 (16.7%) | 18 (40.0%) | |
Recurrence | n = 105 | 0.90 | ||
0 | 59 | 28 (58.3%) | 30 (53.6%) | |
1 | 32 | 13 (27.1%) | 19 (33.9%) | |
2 | 10 | 5 (10.4%) | 5 (8.9%) | |
≥ 3 | 4 | 2 (4.2%) | 2 (3.6%) | |