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Fig. 4 | BMC Women's Health

Fig. 4

From: Postmenopausal hyperandrogenism due to an ovarian sex cord-stromal tumour causing elevated dehydroepiandrosterone sulphate: a case report

Fig. 4

Steps of androgen synthesis. Synthesis of dehydroepiandrosterone (DHEA), androstenedione, and testosterone are common to both adrenal and ovary. Conversion of DHEA to dehydroepiandrosterone sulphate (DHEAS) is specific to the adrenal cortex. Conversion of testosterone to dihydrotestosterone is seen in peripheral tissues. CYP11A—P450 side-chain cleavage enzyme, CYP17A1—17α hydroxylase, HSD3B2—3β hydroxysteroid dehydrogenase type 2, SULT2A1—sulfotransferase 2A1

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BMC Women's Health

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