Table 4 Genotype and allele frequencies of the IL-1 Ra VNTR polymorphism between women with and without endometriosis
IL-1Ra | n | Genotype n (%) | Allele frequency n (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
*1*1 | *1*2 | *1*3 | *1*4 | *2*2 | *1*3 + *1*4 | *1*2 + *2*2 | 1 | 2 | 3 | 4 | ||
Women without endometriosis | 186 | 90 (48.4) | 55 (29.6) | 10 (5.4) | 8 (4.3) | 23 (12.4) | 18 (9.7) | 78 (41.9) | 253 (68.0) | 101 (27.2) | 10 (2.7) | 8 (2.1) |
Women with endometriosis | 183 | 129 (70.5) | 25 (13.7) | 4 (2.2) | 5 (2.7) | 20 (10.9) | 9 (4.9) | 45 (24.6)1 | 292 (79.8) | 65 (17.8)7 | 4 (1.1) | 5 (1.3) |
Stage I | 63 | 45 (71.4) | 6 (9.5) | 2 (3.2) | 1 (1.6) | 9 (14.3) | 3 (4.8) | 15 (23.8)2 | 99 (78.6) | 24 (19.0)8 | 2 (1.6) | 1 (0.8) |
Stage II | 54 | 39 (72.2) | 9 (16.7) | 1 (1.8) | 2 (3.7) | 3 (5.6) | 3 (5.6) | 12 (22.2)3 | 90 (83.3) | 15 (13.9)9 | 1 (0.9) | 2 (1.9) |
Stage I/II | 117 | 84 (71.8) | 15 (12.8) | 3 (2.6) | 3 (2.6) | 12 (10.3) | 6 (5.1) | 27 (23.1)4 | 189 (80.8) | 39 (16.7)10 | 3 (1.3) | 3 (1.3) |
Stage III | 42 | 31 (73.8) | 7 (16.7) | 2 (4.8) | 0 (0.0) | 2 (4.7) | 2 (4.8) | 9 (21.4)5 | 71 (84.5) | 11 (13.1)11 | 2 (1.2) | 0 (0.0) |
Stage IV | 24 | 14 (58.3) | 3 (12.5) | 1 (4.2) | 0 (0.0) | 6 (25.0) | 1 (4.2) | 9 (37.5) | 32 (66.7) | 15 (31.2) | 1 (2.1) | 0 (0.0) |
Stage III/IV | 66 | 45 (68.2) | 10 (15.2) | 3 (4.5) | 0 (0.0) | 8 (12.1) | 3 (4.5) | 18 (27.3)6 | 103 (78.0) | 26 (19.7)12 | 3 (2.3) | 0 (0.0) |