Table 1 Comparison of clinic-pathological factors between different Silva patterns
Characteristics | Pattern A (N = 96) | Pattern B (N = 90) | Pattern C (N = 159) | p value |
|---|---|---|---|---|
Age | 0.053 | |||
Mean ± SD | 44.8 ± 9.9 | 45.7 ± 8.9 | 47.8 ± 10.6 | |
FIGO stage (%) | < 0.001 | |||
Stage 1 | 93 (96.9) | 86 (95.6) | 130 (81.8) | |
Stage 2 | 3 (3.1) | 4 (4.4) | 29 (18.2) | |
Comorbidity (%) | 0.904 | |||
No | 85 (88.5) | 78 (86.7) | 138 (86.8) | |
Yes | 11 (11.5) | 12 (13.3) | 21 (13.2) | |
Adjuvant treatment (%) | < 0.001 | |||
No | 69 (71.9) | 42 (46.7) | 32 (65.9) | |
Yes | 27 (28.1) | 48 (53.3) | 127 (79.9) | |
HPV infect (%) | 0.004 | |||
No | 1 (1) | 2 (2.2) | 9 (5.7) | |
Yes | 29 (30.2) | 41 (45.6) | 39 (24.5) | |
Unknown | 66 (68.8) | 47 (52.2) | 111 (69.8) | |
LEEP (%) | 0.403 | |||
No | 91 (94.8) | 85 (94.4) | 155 (97.5) | |
Yes | 5 (5.2) | 5 (5.6) | 4 (2.5) | |
Surgical approach (%) | 0.033 | |||
Laparoscopy | 88 (91.7) | 86 (95.6) | 136 (85.5) | |
Laparotomy | 8 (8.3) | 4 (4.4) | 23 (14.5) | |
Surgical duration, min (%) | 0.23 | |||
≤ 200 | 50 (52.1) | 56 (62.2) | 82 (51.6) | |
> 200 | 46 (47.9) | 34 (37.8) | 77 (48.4) | |
Blood loss, ml (%) | 0.943 | |||
≤ 200 | 51 (53.1) | 49 (54.4) | 83 (52.2) | |
> 200 | 45 (46.9) | 41 (45.6) | 76 (47.8) | |
Transfusion (%) | 0.186 | |||
No | 93 (96.9) | 82 (91.1) | 145 (91.2) | |
Yes | 3 (3.1) | 8 (8.9) | 14 (8.8) | |
LN metastasis (%) | < 0.001 | |||
No | 94 (97.9) | 85 (94.4) | 109 (68.6) | |
Yes | 2 (2.1) | 5 (5.6) | 50 (31.4) | |
Metastasis site (%) | < 0.001 | |||
No | 94 (97.9) | 85 (94.4) | 109 (68.6) | |
Pelvic LN | 2 (2.1) | 5 (5.6) | 32 (20.1) | |
Common iliac LN | 0 (0) | 0 (0) | 15 (9.4) | |
Para-aortic LN | 0 (0) | 0 (0) | 3 (1.9) | |
Surgical margin (%) | 0.043 | |||
No | 94 (97.9) | 89 (98.9) | 148 (93.1) | |
Yes | 2 (2.1) | 1 (1.1) | 11 (6.9) | |
Parametrial invasion (%) | < 0.001 | |||
No | 96 (100) | 89 (98.9) | 140 (88.1) | |
Yes | 0 (0) | 1 (1.1) | 19 (11.9) | |
Tumor size, cm (%) | < 0.001 | |||
≤ 2 | 72 (75) | 50 (55.6) | 32 (20.1) | |
(2,4) | 23 (24) | 33 (36.7) | 90 (56.6) | |
> 4 | 1 (1) | 7 (7.8) | 37 (23.3) | |
LVSI (%) | < 0.001 | |||
No | 96 (100) | 67 (74.4) | 63 (39.6) | |
Mild | 0 (0) | 22 (24.4) | 56 (35.2) | |
Substantial | 0 (0) | 1 (1.1) | 40 (25.2) | |
DSI (%) | < 0.001 | |||
No | 28 (29.2) | 10 (11.1) | 12 (7.5) | |
< 2/3 | 61 (63.5) | 55 (61.1) | 27 (17) | |
≥ 2/3 | 7 (7.3) | 25 (27.8) | 120 (75.5) | |
PNI (%) | 0.002 | |||
No | 96 (100) | 87 (96.7) | 143 (89.9) | |
Yes | 0 (0) | 3 (3.3) | 16 (10.1) |