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Table 1 Basal clinical characteristics of the study population

From: Gonadotropin-releasing hormone agonist for the preservation of ovarian function in survivors of haematopoietic stem cell transplantation for haematological diseases

 

GnRHa(107)

Control(204)

P

Age(years)

22.86 ± 6.59

23.49 ± 6.85

0.435

Diagnosis for HSCT

 Lymphoblastic leukemia

32(29.91)

87(42.65)

0.001

 Myeloid leukemia

32(29.91)

77(37.75)

 

 Aplastic anemia

28(26.17)

17(8.33)

 

 Myelodysplastic syndrome

13(12.15)

19(9.31)

 

 Others

2(1.87)

4(1.96)

 

Conventional chemotherapy prior to the myeloablative regimen for HSCT

 Yes

69(64.49)

170(83.33)

< 0.001

 No

38(35.51)

34(16.67)

 

TBI exposure

 Yes

2(1.87)

8(3.92)

0.330

 No

105(98.13)

196(96.08)

 

Alkylator agent exposure

107(100.00)

204(100.00)

/

Pre-transplantation FSH(mIU/ml)

8.86 ± 5.27

9.31 ± 4.60

0.338

Pre-transplantation LH(mIU/ml)

8.39 ± 6.13

7.45 ± 3.35

0.403

Pre-transplantation E2(pg/ml)

82.27 ± 60.43

78.90 ± 37.08

0.614

  1. HSCT Hematopoietic stem cell transplantation, TBI Total body irradiation, FSH Follicle-stimulating hormone, LH Luteinizing hormone, E2 Estradiol