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Table 1 Comparative properties of three-progestin-only contraceptive methods used in this study

From: Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): a prospective cohort study protocol

 

Depot Medroxyprogesterone Acetate (DMPA)

Levonorgestrel IUD

Etonogestrel Implant

Trade-name

DepoProvera

Liletta

Nexplanon

Progestin

Medroxyprogesterone acetate (MPA) 1st generation

Levonorgestrel (LNG) 2nd generation

Etonogestrel (ENG) 3rd generation

Delivery

Intramuscular Injection

Intrauterine Device

Sub-dermal Implant

Length of Use

3 months

6 years

3 years

Global Utilization

High

Low

Low

Ovulation Inhibition

High

Low

High

Endogenous estrogen inhibition

Yes

No

Some initially