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Table 2 Molecular subtypes of breast cancer in patients younger than 40 years) and forty years or older

From: Clinicopathologic characteristics of early-onset breast cancer: a comparative analysis of cases from across Ghana

 

Age group in years

p-value

 < 40

 ≥ 40

Molecular subtype

Luminal A

55 (11.30%)

209 (10.80%)

0.78

Luminal B (HER2 positive)

46 (9.40%)

182 (9.40%)

0.998

Luminal B (HER2 negative)

93 (19.10%)

427 (22.10%)

0.141

HER2-enriched

54 (11.10%)

225 (11.70%)

0.715

TNBC

129 (26.40%)

469 (24.30%)

0.329

Others

111 (22.70%)

418 (21.70%)

0.604

Total

488 (100%)

1930 (100%)

0.476

Receptor status versus HER2 equivocal

Positive (ER+/PR+, ER−/PR+, ER+/PR−)

61 (55.00%)

257 (61.50%)

0.213

Negative (ER−/PR−)

50 (45.00%)

161 (38.50%)

 

Total

111 (100%)

418 (100%)

 
  1. ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor-2