Fig. 5From: Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathwayKisspeptin induces the activation of PI3K/AKT/ERK signalling pathway. KGN cells were transfected with KISS-1-overexpressing vectors (A), shRNAs targeting KISS-1 (B), or the negative controls. The phosphorylated and total levels of PI3K, AKT, and ERK were measured by western blotting. *P < 0.05, **P < 0.01, ***P < 0.001Back to article page