Table 3 Comparison of clinical and laboratory characteristics pre-treatment and post treatment in cases (OCP group) versus controls (drug naive group)
Variables | OCP group (Cases) | Drug naive group (Controls) | P value | |
|---|---|---|---|---|
Mean ± SD N = 25 Pre treatment | Mean ± SD N = 25 Post treatment | Mean ± SD N = 25 | ||
Age(years) | 24.8 ± 1.20 | 24.8 ± 1.20 | 24.25 ± 1.48 | 0.23 |
FG Score | 13.3 ± 4.4 | 10.26 ± 5.57 | 15.58 ± 2.99 | 0.003 |
No. of cycles per year | 7.3 ± 2.2 | 11.87 ± 2.9 | 6.8 ± 3.4 | 0.001 |
BMI (kg/m2) | 23.7 ± 1.12 | 24.70 ± 1.66 | 23.9 ± 2.21 | 0.101 |
Waist Hip Ratio | 0.87 ± 0.01 | 0.89 ± 0.03 | 0.87 ± 0.02 | 0.001 |
SBP (mmHg) | 121.87 ± 1.73 | 129 ± 0.53 | 121.41 ± 1.72 | 0.001 |
DBP (mmHg) | 82.07 ± 1.15 | 85.8 ± 0.83 | 81.08 ± 1.16 | 0.001 |
LH(IU/l) | 6.03 ± 1.83 | 5.8 ± 2.48 | 6.05 ± 1.63 | 0.887 |
FSH(IU/l) | 4.56 ± 2.81 | 5.13 ± 2.28 | 4.12 ± 2.31 | 0.357 |
Testosterone(ng/dl) | 75.61 ± 3.2 | 44.4 ± 5.99 | 79.66 ± 4.20 | 0.001 |
Blood glucose fasting (mg/dl) | 84.21 ± 5.22 | 89.90 ± 10.5 | 86.25 ± 5.72 | 0.03 |
Blood glucose 1 h (mg/dl) | 143.6 ± 1.3 | 173 ± 1.13 | 141.6 ± 1.26 | 0.001 |
Blood glucose 2 h (mg/dl) | 120.6 ± 5.3 | 145.06 ± 4.44 | 117.66 ± 4.53 | 0.001 |
Insulin fasting (µIU/ml) | 13.35 ± 1.2 | 16.06 ± 4.6 | 12.75 ± 1.35 | 0.002 |
Insulin 1 h (µIU/ml) | 53.02 ± 2.2 | 65.6 ± 2.04 | 55.08 ± 3.43 | 0.001 |
Insulin 2 h (µIU/ml) | 52.60 ± 3.89 | 60.53 ± 13.61 | 51.58 ± 3.89 | 0.005 |
HOMA -IR | 2.77 ± 1.02 | 3.56 ± 1.18 | 2.71 ± 0.17 | 0.001 |
QUICKI | 0.34 ± 0.01 | 0.32 ± 0.02 | 0.34 ± 0.01 | 0.001 |
FGIR | 6.30 ± 0.55 | 5.59 ± 1.02 | 6.76 ± 0.61 | 0.001 |
Cholesterol(mg/dl) | 152.25 ± 7.92 | 194.74 ± 7.25 | 157.25 ± 8.97 | 0.001 |
Triglycerides (mg/dl) | 97.36 ± 4.83 | 148 ± 5.2 | 96.66 ± 5.89 | 0.001 |
HDL-Cholesterol(mg/dl) | 47.36 ± 5.3 | 53 ± 6.59 | 47.06 ± 4.30 | 0.002 |
LDL-Cholesterol(mg/dl) | 97.66 ± 5.53 | 110 ± 12.04 | 96.66 ± 5.89 | 0.001 |