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Table 8 Association of PAI-1 mRNA expression with metabolic indices in cases (post OCP treated OCP group)

From: Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

Gene

Glucose 2 h

Mean ΔCT ± SD

Number

P value

PAI-1

 ≥ 140

11.64 ± 0.9

15

0.008

 < 140

12.54 ± 0.48

10

Triglycerides

  

0.001

 ≥ 150

11.47 ± 0.88

17

 < 150

12.71 ± 0.62

8

  1. PAI-1 Plasminogen activator inhibitor-1, CT Cycle threshold, SD Standard deviation