The average gonadotrophin dosage per follicle is predictive of ovarian response and cumulative live birth chances after in vitro fertilization: a retrospective cohort study

Table 2 Cycle parameters of patients grouped according to average Gn dosage per follicle

N	Group A	Group B	Group C	P
N	110	110	110	P
Initial Gn dose (IU)	199.89 ± 30.41	223.18 ± 33.30	243.64 ± 40.73	< 0.01
Total Gn dose (IU)	1607.44 ± 296.70	1952.96 ± 427.61	2443.64 ± 563.58	< 0.01
Gn duration (days)	9.24 ± 0.94	9.44 ± 1.11	9.97 ± 1.44	< 0.01
LH on day of trigger (IU/L)	2.42 ± 1.73	2.28 ± 1.45	2.74 ± 1.76	0.11
E₂ on day of trigger (pg/ml)	4176.34 ± 1681.63	3207.76 ± 1424.61	2452.90 ± 1154.19	< 0.01
P on day of trigger (ng/ml)	0.81 ± 0.41	0.82 ± 0.41	0.75 ± 0.43	0.46
Endometrial thickness (mm)	10.43 ± 2.33	10.68 ± 2.08	10.63 ± 2.17	0.67
FORT	0.98 ± 0.36	0.77 ± 0.23	0.70 ± 0.26	< 0.01
FOI	1.03 ± 0.46	0.90 ± 0.35	0.93 ± 0.39	0.04
OSI	11.80 ± 4.31	7.34 ± 2.46	4.64 ± 2.09	< 0.01
No. of oocytes	18.52 ± 6.12	14.09 ± 5.04	10.79 ± 4.21	< 0.01
No. of fertilized	14.40 ± 5.86	10.68 ± 4.38	8.41 ± 3.92	< 0.01
No. of 2PN	11.25 ± 5.18	8.64 ± 4.36	6.46 ± 3.65	< 0.01
No. of good quality embryos	4.75 ± 3.57	4.21 ± 3.04	2.86 ± 2.09	< 0.01

Gn gonadotropin, FORT follicular output rate = No. of pre-ovulatory follicles/AFC, FOI follicle-to-oocyte index = No. of oocytes retrieved/AFC, OSI ovarian sensitivity index = number of retrieved oocytes/total Gn dose × 1000; 2PN two pronuclei

ISSN: 1472-6874