Table 3 Genotype and allele frequencies of Interleukin (IL)-6 and IL-16 SNPs in control and endometriosis patients

IL-6 (G > C): rs1800795

n = 62

n = 64

GG

62 (100)

64 (100)

-

IL16 (C/T): rs4778889

n = 62

n = 64

TT

29 (46.8)

19 (29.7)

p = 0.08

TC

27 (43.5)

32 (50)

CC

6 (9.7)

13 (20.3)

TT + TC (vs. CC)^a

56 (90.3)

51 (79.7)

p = 0.095,

2.38 (0.85 – 6.73)

TC + CC (vs. TT)^b

33 (53.2)

45 (70.3)

p = 0.048, 2.08 (0.98 – 4.30)

HWE (p-value)

0.938

0.943

T

85 (69)

70 (55)

p = 0.024

C

39 (31)

58 (45)

1.80 (1.08 – 3.02)

IL16 (T/G): rs11556218

n = 60

n = 62

TT

39 (65.0)

36 (58.1)

p = 0.640

TG

17 (28.3)

23 (37.1)

GG

4 (6.7)

3 (4.8)

TT + TG (vs. GG)^a

56 (93.3)

59 (95.2)

p = 0.664

0.72 (0.17 – 2.76)

TG + GG (vs. TT) ^b

21 (35.0)

26 (41.9)

p = 0.431

0.75 (0.37 – 1.60)

HWE (p-value)

0.275

0.782

T

95 (79)

95 (77)

p = 0.480

G

25 (21)

29 (23)

1.16 (0.63 – 2.13)

IL16 (C/T): rs4072111

n = 60

n = 62

CC

58 (96.7)

55 (88.7)

p = 0.094

CT

2 (3.3)

7 (11.3)

HWE (p-value)

0.896

0.638

C

118 (98)

117 (94)

p = 0.121

T

2 (2)

7 (6)

3.53 (0.72 – 17.35)