Table 2 Association between symptoms of hyperandrogenemia and ovulatory dysfunction, social determinants of health, and comorbidities with the outcome of PCOS category, defined as self-reported PCOS, unrecognized PCOS, or no PCOS. Odds ratios and 95% confidence intervals (OR, 95% CI) shown. All models adjust for age, race (Black vs. White), and field center

Model 1: Symptoms of hyperandrogenism and ovulatory dysfunction

Unwanted hair growth during 20-30 s

4.58 (2.41, 8.7)

17.22 (10.1, 29.35)

Acne during 20-30 s

0.85 (0.45, 1.59)

1.3 (0.79, 2.15)

Irregular menses during 20-30 s

3.70 (1.85, 7.14)

*

OCP use during 20 – 30 s

0.63 (0.32, 1.24)

0.24 (0.13, 0.44)

Model 2: Social determinants of health

Food insecurity

0.93 (0.37, 2.36)

1.94 (1.25, 3.01)

Did not seek care because of cost or lack of coverage

0.97 (0.34, 2.75)

1.2 (0.69, 2.10)

Very hard, fairly hard, not too hard to get health services

1.75 (0.86, 3.56)

1.31 (0.86, 2.01)

Model 3: Comorbidities

BMI category at year 15

1.83 (1.22, 2.75)

1.04 (0.83, 1.3)

Hypertension at year 15

0.75 (0.3, 1.91)

1.68 (1.03, 2.74)

Diabetes at year 15

2.37 (1.05, 5.33)

1.26 (0.7, 2.29)

Model 4: Symptoms, social determinants of health, and comorbidities

Unwanted hair growth during 20-30 s

4.11 (2.13, 7.91)

16.8 (9.72, 29.06)

Acne during 20-30 s

0.87 (0.46, 1.66)

1.38 (0.82, 2.31)

Irregular menses during 20-30 s

3.70 (1.85, 7.69)

^*

OCP use during 20-30 s

0.63 (0.32, 1.25)

0.25 (0.13, 0.46)

Food insecurity

0.77 (0.32, 1.88)

1.73 (0.87, 3.44)

Did not seek care because of cost or lack of coverage

1.14 (0.45, 2.93)

1.38 (0.60, 3.17)

Very hard, fairly hard, not too hard to get health services

1.46 (0.71, 2.98)

0.91 (0.49, 1.7)

BMI category at year 15

1.71 (1.13, 2.59)

1.17 (0.86, 1.60)

Hypertension at year 15

0.76 (0.29, 1.94)

1.60 (0.77, 3.33)

Diabetes at year 15

2.18 (0.95, 5.04)

0.86 (0.37, 1.96)