From: Pre-eclampsia during pregnancy and risk of endometrial cancer: a systematic review and meta-analysis
Sub-group analyses | No. of included studies | Pooled risk estimate (95% CI) | I-squared | P-value (Heterogeneity) |
---|---|---|---|---|
Main analysis | 7 | 1.07 (0.79–1.46) | 34.1% | 0.17 |
Studies with a quality score ≥ 7 | 5 | 1.05(0.72–1.54) | 50.7% | 0.08 |
Studies with a quality score of < 7 | 2 | 0.90(0.39–2.08) | 0.0% | 0.99 |
Restricted to studies adjusting for potential confounding factors | 4 | 1.01(0.61–1.67) | 58.1% | 0.06 |
Risk of endometrial neoplasiaa | 7 | 1.34(1.15–1.57) | 29.6% | 0.20 |
Summary of pooled results removing individual studies investigating pre-eclampsia and risk of endometrial cancer | ||||
Excluding Liu et al. (2021) | 6 | 1.06(0.75–1.48) | 42.9% | 0.12 |
Excluding Trabert et al. (2020) | 6 | 0.85(0.60–1.21) | 0% | 0.92 |
Excluding Cho et al. (2019) | 6 | 1.12(0.84–1.49) | 31.7% | 0.19 |
Excluding Walfisch et al. (2015) | 6 | 1.07(0.76–1.50) | 40.8% | 0.13 |
Excluding Bhattacharya et al. (2012) | 6 | 1.40(1.26–1.54) | 0% | 0.42 |
Excluding Calderon-Margalit et al. (2009 | 6 | 1.07(0.76–1.51) | 39.1% | 0.15 |
Excluding Mogren et al. (2001) | 6 | 1,04(0.71–1.52) | 38.9% | 0.15 |