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Gynecology, gynecological disease, and reproductive health

Section edited by Aleksandra Gentry-Maharaj, and Zephne van der Spuy

This section considers studies regarding all aspects of gynecology and reproductive health, including cervical cancer, ovarian cancer, fertility, contraception, abortion, menarche, menstruation, and menopause.

Page 1 of 4

  1. Content type: Research article

    Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL). To date, there is no data on p...

    Authors: Kitirat Techatraisak, Andon Hestiantoro, Soon Ruey, Maria Jesusa Banal-Silao, Mee-Ran Kim, Seok Ju Seong, Syarief Thaufik, Christiane Ahlers, So Young Shin and Byung Seok Lee

    Citation: BMC Women's Health 2019 19:68

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  2. Content type: Case report

    Ovarian insufficiency is a major concern for long-term cancer survivors. Although semen freezing is well established to preserve male fertility, the possibilities to secure post-cancer female fertility are mos...

    Authors: Triin Tammiste, Keiu Kask, Peeter Padrik, Külli Idla, Karin Rosenstein, Tatjana Jatsenko, Piret Veerus and Andres Salumets

    Citation: BMC Women's Health 2019 19:65

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  3. Content type: Research article

    Endometriosis is a chronic disease impacting on many aspects of a woman’s life. Because of the chronic and recurring nature, many of the impacts of endometriosis could be missed using existing questionnaires w...

    Authors: Maryam Moradi, Melissa Parker, Anne Sneddon, Violeta Lopez and David Ellwood

    Citation: BMC Women's Health 2019 19:64

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  4. Content type: Research article

    A high endogenous progesterone luteal state in the menstrual cycle has been independently associated with Human Immunodeficiency Virus (HIV) incidence in epidemiological studies. Hormonal contraception particu...

    Authors: Resha Boodhram, Dhayendre Moodley, Nathlee Abbai and Gita Ramjee

    Citation: BMC Women's Health 2019 19:63

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  6. Content type: Research article

    The recurrence rate after unilateral salpingo-oophorectomy (USO) for unilateral endometrioma has not been reported. We evaluated the rate of and risk factors for endometrioma recurrence after USO.

    Authors: Tokie Hidari, Tetsuya Hirata, Tomoko Arakawa, Kaori Koga, Kazuaki Neriishi, Shinya Fukuda, Akari Nakazawa, Natsuki Nagashima, Suke Ma, Hui Sun, Masashi Takamura, Miyuki Harada, Yasushi Hirota, Osamu Wada-Hiraike, Tomoyuki Fujii and Yutaka Osuga

    Citation: BMC Women's Health 2019 19:59

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  7. Content type: Research article

    Studies have demonstrated that women with low desire and low excitement have negative feelings regarding their physical and emotional satisfaction, as well as their happiness. In this study, we evaluate the ef...

    Authors: S. Palacios, E. Soler, M. Ramírez, M. Lilue, D. Khorsandi and F. Losa

    Citation: BMC Women's Health 2019 19:58

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  8. Content type: Research article

    The ovarian reserve in women is known to correlate with anti-Müllerian hormone (AMH) levels, and currently the latest, third-generation, fully-automated AMH immunoassays, such as Access and Cobas, are beginnin...

    Authors: Tomoya Segawa, Kenji Omi, Yoshiaki Watanabe, Yaeko Sone, Masaki Handa, Masako Kuroda, Osamu Miyauchi, Hisao Osada and Shokichi Teramoto

    Citation: BMC Women's Health 2019 19:57

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  9. Content type: Research article

    Individuals born very preterm or with very low birth weight (VLBW) have a reduced likelihood to reproduce according to population-based register studies. Extremely low-birth weight born adults had a lower repr...

    Authors: Gunilla Sydsjö, Pia Törnblom, P-O Gäddlin, Orvar Finnström, Ingemar Leijon, Nina Nelson, Elvar Theodorsson and Mats Hammar

    Citation: BMC Women's Health 2019 19:56

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  10. Content type: Research article

    The incidence of Pelvic Organ Prolapse (POP) in the developing world is not known. A nonclinical screening tool for prolapse is needed in the resource poor setting. In this study, we aim to determine the valid...

    Authors: Dawit Worku Kassa, Yirgu Gebrehiwot Ferede and Polina Advolodkina

    Citation: BMC Women's Health 2019 19:52

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  11. Content type: Study protocol

    There is lack of population level data on prevalence and distribution of common benign women’s health conditions such as endometriosis, uterine fibroids, polycystic ovary syndrome from the Eastern Mediterranea...

    Authors: M. B. Hocaoglu, S. Gurkas, T. Karaderi, B. Taneri, K. Erguler, B. Barin, E. M. Bilgin, G. Eralp, M. Allison, N. Findikli, K. Boynukalin, M. Bahceci, H. Naci, K. Vincent, S. A. Missmer, C. M. Becker…

    Citation: BMC Women's Health 2019 19:50

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  12. Content type: Study protocol

    Pelvic organ prolapse (POP) affects up to 40% of parous women which adversely affects the quality of life. During a life time, 20% of all women will undergo an operation. In general the guidelines advise a vag...

    Authors: Sascha F. M. Schulten, Rosa A. Enklaar, Kirsten B. Kluivers, Sanne A. L. van Leijsen, Marijke C. Jansen-van der Weide, Eddy M. M. Adang, Jeroen van Bavel, Heleen van Dongen, Maaike B. E. Gerritse, Iris van Gestel, G. G. Alec Malmberg, Ronald J. C. Mouw, Deliana A. van Rumpt-van de Geest, Wilbert A. Spaans, Annemarie van der Steen, Jelle Stekelenburg…

    Citation: BMC Women's Health 2019 19:49

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  13. Content type: Research article

    Vulvovaginal candidiasis (VVC) is a common infection affecting women worldwide. Reports of patterns/risk factors/trends for episodic/recurrent VVC (RVVC) are largely outdated. The purpose of this study was to ...

    Authors: Junko Yano, Jack D. Sobel, Paul Nyirjesy, Ryan Sobel, Valerie L. Williams, Qingzhao Yu, Mairi C. Noverr and Paul L. Fidel Jr

    Citation: BMC Women's Health 2019 19:48

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  14. Content type: Technical advance

    European guidelines for cervical cancer screening now recommend the use of clinically validated assays for high-risk HPV-DNA sequences as primary test in women older than 30 years, performed in centralized lab...

    Authors: Helena Frayle, Silvia Gori, Martina Rizzi, Bianca Nives Graziani, Elisa Vian, Paolo Giorgi Rossi and Annarosa Del Mistro

    Citation: BMC Women's Health 2019 19:47

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  15. Content type: Study protocol

    In women with abnormal uterine bleeding, fibroids are a frequent finding. In case of heavy menstrual bleeding and presence of submucosal type 0–1 fibroids, hysteroscopic resection is the treatment of first cho...

    Authors: Julia F. van der Meulen, Marlies Y. Bongers, Sjors F. P. J. Coppus, Judith E. Bosmans, José M. C. Maessen, Katrien Oude Rengerink, Lucilla E. Overdijk, Celine M. Radder, Lucet F. van der Voet, Nicol A. C. Smeets, Huib A. A. M. van Vliet, Wouter J. K. Hehenkamp, Arentje P. Manger, Wilbert A. Spaans, Erica A. Bakkum, Nicole Horrée…

    Citation: BMC Women's Health 2019 19:46

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  16. Content type: Research article

    Pelvic organ prolapse is a common urogenital condition affecting 41–50% of women over the age of 40. To achieve early diagnosis and appropriate treatment, it is important that care is sensitive to and meets wo...

    Authors: Purva Abhyankar, Isabelle Uny, Karen Semple, Sarah Wane, Suzanne Hagen, Joyce Wilkinson, Karen Guerrero, Douglas Tincello, Edward Duncan, Eileen Calveley, Andrew Elders, Doreen McClurg and Margaret Maxwell

    Citation: BMC Women's Health 2019 19:45

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  17. Content type: Research article

    In the Democratic Republic of Congo (DRC), practical and affordable strategies for cervical cancer screening are needed to detect and treat pre-cancerous and cancerous lesions in a timely fashion. This study p...

    Authors: Justin Lussy Paluku, Tamar E. Carter, Miriam Lee and Susan A Bartels

    Citation: BMC Women's Health 2019 19:43

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  18. Content type: Research article

    One of the leading cause of maternal mortality and morbidity is unsafe abortion. Globally 55.7million of abortions occurred each year between 2010 and 2014. In lower resource countries 24.3 million abortions w...

    Authors: Jamuna Tamrakar Sayami

    Citation: BMC Women's Health 2019 19:41

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  19. Content type: Research article

    Obstetric fistula is a hole between the vagina and bladder, and/or between the vagina and rectum, triggered by prolonged obstructed labor. The World Health Organization has estimated that at least 50,000 to 10...

    Authors: Misganaw Animut, Abebe Mamo, Lakew Abebe, Million Abera Berhe, Shifera Asfaw and Zewdie Birhanu

    Citation: BMC Women's Health 2019 19:37

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  20. Content type: Research article

    Vaginal douching is a common practice among women all over the world. Women douche for various reasons, despite evidence indicating the harmful health effects of the practice. There is lack of data on the prac...

    Authors: Florence Assibi Ziba, Vida Nyagre Yakong, Rockson Asaan Asore, Keville Frederickson and Michele Flynch

    Citation: BMC Women's Health 2019 19:32

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  22. Content type: Research article

    Local treatment for cervical intraepithelial neoplasia (CIN) by Loop Electrosurgical Excision Procedure (LEEP) has been correlated with reproductive morbidity, while the cervicovaginal microbiota is also known...

    Authors: Johanna Wiik, Verena Sengpiel, Maria Kyrgiou, Staffan Nilsson, Anita Mitra, Tom Tanbo, Christine Monceyron Jonassen, Tone Møller Tannæs and Katrine Sjøborg

    Citation: BMC Women's Health 2019 19:30

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  23. Content type: Research article

    Heavy menstrual bleeding (HMB) has been shown to have a profound negative impact on women’s quality of life and lead to increases in health care costs; however, data on HMB among Chinese population is still ra...

    Authors: Chengyi Ding, Jing Wang, Yu Cao, Yuting Pan, Xueqin Lu, Weiwei Wang, Lin Zhuo, Qinjie Tian and Siyan Zhan

    Citation: BMC Women's Health 2019 19:27

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  24. Content type: Research article

    The use of long-acting and permanent method (LAPM) for family planning (FP) is of importance to the FP movement. A better understanding of how fertility-related intentions shape the usage of LAPM is important ...

    Authors: Joshua Amo-Adjei, Michael Mutua, Carol Mukiira, Namuunda Mutombo, Sherine Athero, Alex Ezeh and Chimaraoke Izugbara

    Citation: BMC Women's Health 2019 19:26

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  25. Content type: Debate

    Probiotics are live microorganisms that, when administered in adequate amounts, should confer a health benefit to the host. Media sources tend to present probiotics as an appealing health promotion method able...

    Authors: Laura Buggio, Edgardo Somigliana, Alessandra Borghi and Paolo Vercellini

    Citation: BMC Women's Health 2019 19:25

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  26. Content type: Research article

    The family planning component of postabortion care (PAC) is critical, as it helps women to prevent unintended pregnancies and reduce future incidence of life-threatening unsafe abortion. In Tanzania, PAC was r...

    Authors: Colin Baynes, J. Kahwa, G. Lusiola, F. Mwanga, J. Bantambya, L. Ngosso and M. Hiza

    Citation: BMC Women's Health 2019 19:22

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  28. Content type: Research article

    SNF5 is a key protein in regulating cell proliferation and apoptosis in various cancers. However, the physiological roles of SNF5 in Endometrial carcinoma (EC), which is one of the most frequent malignancies o...

    Authors: Shiying Sun, Yi Wu, Kai Zeng and Yue Zhao

    Citation: BMC Women's Health 2019 19:16

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  29. Content type: Research article

    Cesarean scar endometriosis (CSE) is the most common type of abdominal wall endometriosis (AWE). The aim of this study was to systematically identify the clinical features of CSE and recommend precautionary me...

    Authors: Ping Zhang, Yabing Sun, Chen Zhang, Yeping Yang, Linna Zhang, Ningling Wang and Hong Xu

    Citation: BMC Women's Health 2019 19:14

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  30. Content type: Research article

    Because it is difficult to diagnose accurately whether uterine corporeal mesenchymal tumors are benign or malignant before surgery, an understanding of the characteristics of patients with uterine sarcomas occ...

    Authors: Yumi Ishidera, Hiroshi Yoshida, Yuka Oi, Kayo Katayama, Etsuko Miyagi, Hiroyuki Hayashi and Hiroyuki Shigeta

    Citation: BMC Women's Health 2019 19:13

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  31. Content type: Research article

    Polycystic ovarian syndrome (PCOS) is of frequent occurrence in Saudi females and is often associated with obesity, insulin resistance, hypogonadotropic hypogonadism, and infertility. Since these features are ...

    Authors: Maha H. Daghestani, Mazin H. Daghestani, Mamoon H. Daghistani, Geir Bjørklund, Salvatore Chirumbolo and Arjumand Warsy

    Citation: BMC Women's Health 2019 19:10

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  32. Content type: Research article

    Cervical cancer in Saudi Arabia is ranked as the third most frequent gynecological cancer among women. The Pap smear test is a screening test that can be used as a primary prevention tool for cervical cancer, ...

    Authors: Arwa I. Aldohaian, Sulaiman A. Alshammari and Danyah M. Arafah

    Citation: BMC Women's Health 2019 19:6

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  33. Content type: Research article

    Obstetric fistula is an abnormal connection between the vagina and rectum and/or bladder, which leads to continuous urinary or fecal incontinence. It is a serious problem in the world poorest countries, where ...

    Authors: Leltework Yismaw, Kassahun Alemu, Abebaw Addis and Muluneh Alene

    Citation: BMC Women's Health 2019 19:5

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  34. Content type: Research article

    HPV DNA is found in almost 80% of VIN/VaIN. Current management is inadequate, with high recurrence rates. Our objective was to review the literature regarding the role of HPV vaccine in secondary prevention an...

    Authors: Stacey Bryan, Cynthia Barbara, Jane Thomas and Adeola Olaitan

    Citation: BMC Women's Health 2019 19:3

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  35. Content type: Research article

    Cancer screening programs hold much potential for reducing the cervical cancer disease burden in developing countries. The aim of this study was to determine the feasibility of mobile health (mHealth) phone te...

    Authors: Jennifer Moodley, Deborah Constant, Matthys H. Botha, Frederick H. van der Merwe, Amanda Edwards and Mariette Momberg

    Citation: BMC Women's Health 2019 19:2

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  36. Content type: Research article

    To compare potential factors associated with deep infiltrating endometriosis (DIE) versus ovarian endometrioma (OMA) among endometriosis patients in China.

    Authors: Yi Dai, Yingfang Zhou, Xinmei Zhang, Min Xue, Pengran Sun, Jinhua Leng and Charles Chapron

    Citation: BMC Women's Health 2018 18:205

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  37. Content type: Research article

    The purpose of this comprehensive meta-analysis was to assess the association of aldehyde dehydrogenase (ALDH) expression with overall survival (OS) and disease-free survival (DFS)/progression-free survival (P...

    Authors: Yan Xia, Xuemin Wei, Hui Gong and Yunxiang Ni

    Citation: BMC Women's Health 2018 18:199

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  38. Content type: Case report

    Early diagnosis and efficient management of Chronic Endometritis (CE) in patients seeking fertility treatment are two components every practitioner wishes to address. With respect to endometrial restoration, a...

    Authors: Konstantinos Sfakianoudis, Mara Simopoulou, Yorgos Nikas, Anna Rapani, Nikolaos Nitsos, Katerina Pierouli, Athanasios Pappas, Agni Pantou, Christina Markomichali, Michael Koutsilieris and Konstantinos Pantos

    Citation: BMC Women's Health 2018 18:197

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  39. Content type: Study protocol

    Lifestyle, in particular obesity and smoking has significant impacts on fertility and an important focus for the treatment of reproductive failures is the optimisation of periconceptional lifestyle behaviours....

    Authors: Ka Ying Bonnie Ng, Susan Wellstead, Ying Cheong and Nick Macklon

    Citation: BMC Women's Health 2018 18:196

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  40. Content type: Research article

    To investigate the impact of follicular flushing on the number of oocytes retrieved and embryo quality and to determine the optimal number of flushings for poor ovarian responders (PORs) undergoing in vitro fe...

    Authors: Yu Xiao, Yong Wang, Min Wang and Kai Liu

    Citation: BMC Women's Health 2018 18:186

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  41. Content type: Research article

    Individuals with high sexual compulsivity are preoccupied with their sexual desire to such an extent that it interferes with their normal daily life and can inhibit self-control. Previous studies have found a ...

    Authors: Mengyun Luo, Liping Zhu, Yuanyuan Dong, Zezhou Wang, Qiuming Shen, Dandan Mo, Li Du, Zhiruo Zhang and Yong Cai

    Citation: BMC Women's Health 2018 18:181

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  42. Content type: Research article

    To combine results from a randomized controlled study (RCT) and an observational study (OS) to evaluate discontinuation rate of a levonorgestrel-containing intrauterine contraceptive device (LNG IUD) in a real...

    Authors: Tatsiana Vaitsiakhovich, Anna Filonenko, Richard Lynen, Jan Endrikat and Christoph Gerlinger

    Citation: BMC Women's Health 2018 18:180

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  43. Content type: Research article

    The current estimates of the prevalence of primary ovarian insufficiency (POI) are very variable, but are in most studies believed to be around 1%. It is also very likely tat the prevalence of POI differs betw...

    Authors: Katarina Lagergren, Mats Hammar, Elizabeth Nedstrand, Marie Bladh and Gunilla Sydsjö

    Citation: BMC Women's Health 2018 18:175

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  44. Content type: Research article

    We evaluated the effect of transvaginal mesh (TVM) surgery for voiding function and continence using noninvasive examination and questionnaire. The present study aimed to ascertain which categories of patients...

    Authors: Shohei Kawaguchi, Kazutaka Narimoto, Satoko Urata, Masami Takeyama, Yoshifumi Kadono and Atsushi Mizokami

    Citation: BMC Women's Health 2018 18:174

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  45. Content type: Research article

    Vaginal microbicides are a promising means to prevent the transmission of HIV and other sexually transmitted infections, by empowering women to initiate use prophylactically when they perceive themselves to be...

    Authors: Toral Zaveri, Kimberly A Powell, Kate M Guthrie, Alyssa J Bakke, Gregory R Ziegler and John E Hayes

    Citation: BMC Women's Health 2018 18:170

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  46. Content type: Case report

    Morcellation of undiagnosed uterine sarcoma is cause of abdominal/pelvic dissemination, residual tumor and recurrence. In the preoperative evaluation of suspect uterine masses, magnetic resonance imaging (MRI)...

    Authors: Antonio Mollo, Antonio Raffone, Antonio Travaglino, Annalisa Di Cello, Gabriele Saccone, Fulvio Zullo and Giuseppe De Placido

    Citation: BMC Women's Health 2018 18:169

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  47. Content type: Research article

    A unique standardized national dataset on adolescent girls (21 regions) participating in the Italian Health Behaviour in School-aged Children Study (HBSC) was used to investigate the correlation between body m...

    Authors: Giacomo Lazzeri, Claudia Tosti, Andrea Pammolli, Gianmarco Troiano, Alessio Vieno, Natale Canale, Paola Dalmasso, Patrizia Lemma, Alberto Borraccino, Felice Petraglia and Stefano Luisi

    Citation: BMC Women's Health 2018 18:168

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  48. Content type: Study protocol

    A septate uterus is a uterine anomaly that may affect reproductive outcome, and is associated with an increased risk for miscarriage, subfertility and preterm birth. Resection of the septum is subject of debat...

    Authors: J. F. W. Rikken, C. R. Kowalik, M. H. Emanuel, M. Y. Bongers, T. Spinder, J. H. de Kruif, K. W. M. Bloemenkamp, F. W. Jansen, S. Veersema, A. G. M. G. J. Mulders, A. L. Thurkow, K. Hald, A. Mohazzab, Y. Khalaf, T. J. Clark, M. Farrugia…

    Citation: BMC Women's Health 2018 18:163

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  50. Content type: Research article

    Abortion rate in Ukraine is high and the use of effective contraceptive methods is low. Aiming to explore women’s knowledge and attitudes towards modern contraceptive methods, we performed a survey among women...

    Authors: Volodymyr Podolskyi, Kristina Gemzell-Danielsson and Lena Marions

    Citation: BMC Women's Health 2018 18:159

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