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Gynecology, gynecological disease, and reproductive health

Section edited by Aleksandra Gentry-Maharaj, and Zephne van der Spuy

This section considers studies regarding all aspects of gynecology and reproductive health, including cervical cancer, ovarian cancer, fertility, contraception, abortion, menarche, menstruation, and menopause.

Page 1 of 5

  1. Content type: Research article

    Induced abortion is a common undergo in many societies of the world. Every year, around 20 million unsafe abortions are done worldwide. From fragmented studies conducted in Ethiopia, the prevalence of induced ...

    Authors: Kifle Lentiro, Teklemichael Gebru, Abdusemed Worku, Agizie Asfaw, Tigist Gebremariam and Addisu Tesfaye

    Citation: BMC Women's Health 2019 19:115

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  2. Content type: Research article

    Internationally, women with cervical intraepithelial neoplasia (CIN) lack knowledge about their disease, which limits their ability to take responsibility for self-care and creates negative psychosocial effect...

    Authors: Carla Freijomil-Vázquez, Denise Gastaldo, Carmen Coronado and María-Jesús Movilla-Fernández

    Citation: BMC Women's Health 2019 19:112

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  3. Content type: Research article

    This study aims to investigate the difference in vaginal microecology, local immunity and HPV infection among childbearing-age women with different degrees of cervical lesions.

    Authors: Jing-Jing Zheng, Jing-Hui Song, Cong-Xiang Yu, Fei Wang, Peng-Cheng Wang and Jing-Wei Meng

    Citation: BMC Women's Health 2019 19:109

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  4. Content type: Research article

    Probiotics has been shown to be effective in reducing vaginal colonization of pathogenic organisms. The aim of this study was to investigate the influence of probiotic strains Lactobacillus rhamnosus GR-1 and Lac...

    Authors: Yu-Che Ou, Hung-Chun Fu, Chih-Wen Tseng, Chen-Hsuan Wu, Ching-Chou Tsai and Hao Lin

    Citation: BMC Women's Health 2019 19:103

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  5. Content type: Case report

    A persistent low-level elevation of serum human chorionic gonadotropin (hCG) without clinical or radiological evidence of pregnancy or tumors was recently defined as quiescent gestational trophoblastic disease...

    Authors: Yoshiyuki Okada, Shingo Miyamoto, Takashi Mimura, Tetsuya Ishikawa, Akihiko Sekizawa and Koji Matsumoto

    Citation: BMC Women's Health 2019 19:101

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  6. Content type: Research article

    Uterine leiomyomas are often discovered during early pregnancy and in most cases will have no effect on pregnancy outcomes. However, in rare cases uterine leiomyomas may lead to obstetric complications. The ai...

    Authors: Henry Hillel Chill, Gilad Karavani, Talya Rachmani, Uri Dior, Ofer Tadmor and Asher Shushan

    Citation: BMC Women's Health 2019 19:100

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  7. Content type: Research article

    The apical prolapse is probably the most complex form of pelvic organ prolapse (POP). Adequate apical support is essential in the treatment of POP, as it contributes to the support in all vaginal compartments....

    Authors: Katrine Dahl Pedersen, Marie Højriis Storkholm, Karl Møller Bek, Marianne Glavind-Kristensen and Susanne Greisen

    Citation: BMC Women's Health 2019 19:96

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  8. Content type: Case report

    The combination of intrapelvic and extrapelvic endometriosis is a very rare condition in gynecology. Patients with endometriosis involving the sciatic nerve are easily misdiagnosed because they usually present...

    Authors: Liang Yanchun, Zhao Yunhe, Xia Meng, Chen Shuqin, Zhu Qingtang and Yao Shuzhong

    Citation: BMC Women's Health 2019 19:95

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  9. Content type: Research article

    Reproductive history and urogynecological disorders have been associated with limitations in physical function. However, little is known about the relationship between symptoms of urinary incontinence and pelv...

    Authors: Mariana Carmem Apolinário Vieira, Saionara Maria Aires da Câmara, Mayle Andrade Moreira, Catherine McLean Pirkle, Afshin Vafaei and Álvaro Campos Cavalcanti Maciel

    Citation: BMC Women's Health 2019 19:94

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  10. Content type: Research article

    Uterine Fibroids (UFs) growth is ovarian steroid-dependent. Previous studies have shown that estrogen and progesterone play an important role in UF development. However, the mechanism underlying progesterone i...

    Authors: Mona Omar, Archana Laknaur, Ayman Al-Hendy and Qiwei Yang

    Citation: BMC Women's Health 2019 19:92

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  11. Content type: Research article

    The aim of this paper was to conduct a baseline survey of HPV infection in unvaccinated women in Xinjiang Uyghur Autonomous Region before the mass use of HPV vaccine.

    Authors: Jing Wang, Dandan Tang, Kai Wang, Jialu Wang, Zhaoxia Zhang, Yanxia Chen, Xueliang Zhang and Cailing Ma

    Citation: BMC Women's Health 2019 19:90

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  12. Content type: Research article

    Rigorous exercise undertaken by young girls, combined with a negative energetic balance, is related to substantial physiological changes in a competitor’s body, often leading to hormonal imbalance manifested b...

    Authors: Joanna Witkoś and Piotr Wróbel

    Citation: BMC Women's Health 2019 19:87

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  13. Content type: Research article

    Short birth interval is known to have a negative effect on perinatal, neonatal and child health outcomes. In Ethiopia, 29% of births are short birth intervals at less than 24 months. Even though optimum birth ...

    Authors: Solomon Weldemariam Gebrehiwot, Gedamu Abera, Kidist Tesfay and Weyzer Tilahun

    Citation: BMC Women's Health 2019 19:85

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  14. Content type: Research article

    Obstetric fistula is a debilitating condition resulted from poorly (un) managed prolonged obstructed labor. It has significant psychosocial and economic consequences on those affected and their families. Data ...

    Authors: Debrework Tesgera Bashah, Abebaw Gebeyehu Worku, Mezgebu Yitayal and Telake Azale

    Citation: BMC Women's Health 2019 19:84

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  15. Content type: Research article

    There are various surgical approaches of hysterectomy for benign indications. This study aimed to compare vaginal hysterectomy (VH) and laparoscopic hysterectomy (LH) with respect to their complications and op...

    Authors: Seung Hyun Lee, So Ra Oh, Yeon Jean Cho, Myoungseok Han, Jung-Woo Park, Su Jin Kim, Jeong Hye Yun, Sun Yi Choe, Joong Sub Choi and Jong Woon Bae

    Citation: BMC Women's Health 2019 19:83

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  16. Content type: Case report

    The unicornuate uterus is caused by abnormal or failed development of one Müllerian duct. Unicornuate uteri with functioning non-communicating rudimentary horns are susceptible to many gynaecologic and obstetr...

    Authors: Rawan A. Obeidat, Abdelwahab J. Aleshawi, Nour A. Tashtush and Haya Alsarawi

    Citation: BMC Women's Health 2019 19:71

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  17. Content type: Research article

    To determine whether oral norethindrone acetate is superior to combined oral contraceptives (OCP) in delaying menstruation and preventing breakthrough bleeding when started late in the cycle.

    Authors: Joshua Dean, Katherine J. Kramer, Fauzia Akbary, Shaunte Wade, Maik Hüttemann, Jay M. Berman and Maurice-Andre Recanati

    Citation: BMC Women's Health 2019 19:70

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  18. Content type: Case report

    We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successf...

    Authors: Naoya Ishibashi, Toshiya Maebayashi, Mikiko Asai-Sato, Kei Kawana and Masahiro Okada

    Citation: BMC Women's Health 2019 19:69

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  19. Content type: Research article

    Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL). To date, there is no data on p...

    Authors: Kitirat Techatraisak, Andon Hestiantoro, Soon Ruey, Maria Jesusa Banal-Silao, Mee-Ran Kim, Seok Ju Seong, Syarief Thaufik, Christiane Ahlers, So Young Shin and Byung Seok Lee

    Citation: BMC Women's Health 2019 19:68

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  20. Content type: Case report

    Ovarian insufficiency is a major concern for long-term cancer survivors. Although semen freezing is well established to preserve male fertility, the possibilities to secure post-cancer female fertility are mos...

    Authors: Triin Tammiste, Keiu Kask, Peeter Padrik, Külli Idla, Karin Rosenstein, Tatjana Jatsenko, Piret Veerus and Andres Salumets

    Citation: BMC Women's Health 2019 19:65

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  21. Content type: Research article

    Endometriosis is a chronic disease impacting on many aspects of a woman’s life. Because of the chronic and recurring nature, many of the impacts of endometriosis could be missed using existing questionnaires w...

    Authors: Maryam Moradi, Melissa Parker, Anne Sneddon, Violeta Lopez and David Ellwood

    Citation: BMC Women's Health 2019 19:64

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  22. Content type: Research article

    A high endogenous progesterone luteal state in the menstrual cycle has been independently associated with Human Immunodeficiency Virus (HIV) incidence in epidemiological studies. Hormonal contraception particu...

    Authors: Resha Boodhram, Dhayendre Moodley, Nathlee Abbai and Gita Ramjee

    Citation: BMC Women's Health 2019 19:63

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  23. Content type: Research article

    The recurrence rate after unilateral salpingo-oophorectomy (USO) for unilateral endometrioma has not been reported. We evaluated the rate of and risk factors for endometrioma recurrence after USO.

    Authors: Tokie Hidari, Tetsuya Hirata, Tomoko Arakawa, Kaori Koga, Kazuaki Neriishi, Shinya Fukuda, Akari Nakazawa, Natsuki Nagashima, Suke Ma, Hui Sun, Masashi Takamura, Miyuki Harada, Yasushi Hirota, Osamu Wada-Hiraike, Tomoyuki Fujii and Yutaka Osuga

    Citation: BMC Women's Health 2019 19:59

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  24. Content type: Research article

    Studies have demonstrated that women with low desire and low excitement have negative feelings regarding their physical and emotional satisfaction, as well as their happiness. In this study, we evaluate the ef...

    Authors: S. Palacios, E. Soler, M. Ramírez, M. Lilue, D. Khorsandi and F. Losa

    Citation: BMC Women's Health 2019 19:58

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  25. Content type: Research article

    The ovarian reserve in women is known to correlate with anti-Müllerian hormone (AMH) levels, and currently the latest, third-generation, fully-automated AMH immunoassays, such as Access and Cobas, are beginnin...

    Authors: Tomoya Segawa, Kenji Omi, Yoshiaki Watanabe, Yaeko Sone, Masaki Handa, Masako Kuroda, Osamu Miyauchi, Hisao Osada and Shokichi Teramoto

    Citation: BMC Women's Health 2019 19:57

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  26. Content type: Research article

    Individuals born very preterm or with very low birth weight (VLBW) have a reduced likelihood to reproduce according to population-based register studies. Extremely low-birth weight born adults had a lower repr...

    Authors: Gunilla Sydsjö, Pia Törnblom, P-O Gäddlin, Orvar Finnström, Ingemar Leijon, Nina Nelson, Elvar Theodorsson and Mats Hammar

    Citation: BMC Women's Health 2019 19:56

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  27. Content type: Research article

    The incidence of Pelvic Organ Prolapse (POP) in the developing world is not known. A nonclinical screening tool for prolapse is needed in the resource poor setting. In this study, we aim to determine the valid...

    Authors: Dawit Worku Kassa, Yirgu Gebrehiwot Ferede and Polina Advolodkina

    Citation: BMC Women's Health 2019 19:52

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  28. Content type: Study protocol

    There is lack of population level data on prevalence and distribution of common benign women’s health conditions such as endometriosis, uterine fibroids, polycystic ovary syndrome from the Eastern Mediterranea...

    Authors: M. B. Hocaoglu, S. Gurkas, T. Karaderi, B. Taneri, K. Erguler, B. Barin, E. M. Bilgin, G. Eralp, M. Allison, N. Findikli, K. Boynukalin, M. Bahceci, H. Naci, K. Vincent, S. A. Missmer, C. M. Becker…

    Citation: BMC Women's Health 2019 19:50

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  29. Content type: Study protocol

    Pelvic organ prolapse (POP) affects up to 40% of parous women which adversely affects the quality of life. During a life time, 20% of all women will undergo an operation. In general the guidelines advise a vag...

    Authors: Sascha F. M. Schulten, Rosa A. Enklaar, Kirsten B. Kluivers, Sanne A. L. van Leijsen, Marijke C. Jansen-van der Weide, Eddy M. M. Adang, Jeroen van Bavel, Heleen van Dongen, Maaike B. E. Gerritse, Iris van Gestel, G. G. Alec Malmberg, Ronald J. C. Mouw, Deliana A. van Rumpt-van de Geest, Wilbert A. Spaans, Annemarie van der Steen, Jelle Stekelenburg…

    Citation: BMC Women's Health 2019 19:49

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  30. Content type: Research article

    Vulvovaginal candidiasis (VVC) is a common infection affecting women worldwide. Reports of patterns/risk factors/trends for episodic/recurrent VVC (RVVC) are largely outdated. The purpose of this study was to ...

    Authors: Junko Yano, Jack D. Sobel, Paul Nyirjesy, Ryan Sobel, Valerie L. Williams, Qingzhao Yu, Mairi C. Noverr and Paul L. Fidel Jr

    Citation: BMC Women's Health 2019 19:48

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  31. Content type: Technical advance

    European guidelines for cervical cancer screening now recommend the use of clinically validated assays for high-risk HPV-DNA sequences as primary test in women older than 30 years, performed in centralized lab...

    Authors: Helena Frayle, Silvia Gori, Martina Rizzi, Bianca Nives Graziani, Elisa Vian, Paolo Giorgi Rossi and Annarosa Del Mistro

    Citation: BMC Women's Health 2019 19:47

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  32. Content type: Study protocol

    In women with abnormal uterine bleeding, fibroids are a frequent finding. In case of heavy menstrual bleeding and presence of submucosal type 0–1 fibroids, hysteroscopic resection is the treatment of first cho...

    Authors: Julia F. van der Meulen, Marlies Y. Bongers, Sjors F. P. J. Coppus, Judith E. Bosmans, José M. C. Maessen, Katrien Oude Rengerink, Lucilla E. Overdijk, Celine M. Radder, Lucet F. van der Voet, Nicol A. C. Smeets, Huib A. A. M. van Vliet, Wouter J. K. Hehenkamp, Arentje P. Manger, Wilbert A. Spaans, Erica A. Bakkum, Nicole Horrée…

    Citation: BMC Women's Health 2019 19:46

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  33. Content type: Research article

    Pelvic organ prolapse is a common urogenital condition affecting 41–50% of women over the age of 40. To achieve early diagnosis and appropriate treatment, it is important that care is sensitive to and meets wo...

    Authors: Purva Abhyankar, Isabelle Uny, Karen Semple, Sarah Wane, Suzanne Hagen, Joyce Wilkinson, Karen Guerrero, Douglas Tincello, Edward Duncan, Eileen Calveley, Andrew Elders, Doreen McClurg and Margaret Maxwell

    Citation: BMC Women's Health 2019 19:45

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  34. Content type: Research article

    In the Democratic Republic of Congo (DRC), practical and affordable strategies for cervical cancer screening are needed to detect and treat pre-cancerous and cancerous lesions in a timely fashion. This study p...

    Authors: Justin Lussy Paluku, Tamar E. Carter, Miriam Lee and Susan A Bartels

    Citation: BMC Women's Health 2019 19:43

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  35. Content type: Research article

    One of the leading cause of maternal mortality and morbidity is unsafe abortion. Globally 55.7million of abortions occurred each year between 2010 and 2014. In lower resource countries 24.3 million abortions w...

    Authors: Jamuna Tamrakar Sayami

    Citation: BMC Women's Health 2019 19:41

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  36. Content type: Research article

    Obstetric fistula is a hole between the vagina and bladder, and/or between the vagina and rectum, triggered by prolonged obstructed labor. The World Health Organization has estimated that at least 50,000 to 10...

    Authors: Misganaw Animut, Abebe Mamo, Lakew Abebe, Million Abera Berhe, Shifera Asfaw and Zewdie Birhanu

    Citation: BMC Women's Health 2019 19:37

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  37. Content type: Research article

    Vaginal douching is a common practice among women all over the world. Women douche for various reasons, despite evidence indicating the harmful health effects of the practice. There is lack of data on the prac...

    Authors: Florence Assibi Ziba, Vida Nyagre Yakong, Rockson Asaan Asore, Keville Frederickson and Michele Flynch

    Citation: BMC Women's Health 2019 19:32

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  38. Content type: Research article

    Local treatment for cervical intraepithelial neoplasia (CIN) by Loop Electrosurgical Excision Procedure (LEEP) has been correlated with reproductive morbidity, while the cervicovaginal microbiota is also known...

    Authors: Johanna Wiik, Verena Sengpiel, Maria Kyrgiou, Staffan Nilsson, Anita Mitra, Tom Tanbo, Christine Monceyron Jonassen, Tone Møller Tannæs and Katrine Sjøborg

    Citation: BMC Women's Health 2019 19:30

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  39. Content type: Research article

    Heavy menstrual bleeding (HMB) has been shown to have a profound negative impact on women’s quality of life and lead to increases in health care costs; however, data on HMB among Chinese population is still ra...

    Authors: Chengyi Ding, Jing Wang, Yu Cao, Yuting Pan, Xueqin Lu, Weiwei Wang, Lin Zhuo, Qinjie Tian and Siyan Zhan

    Citation: BMC Women's Health 2019 19:27

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  40. Content type: Research article

    The use of long-acting and permanent method (LAPM) for family planning (FP) is of importance to the FP movement. A better understanding of how fertility-related intentions shape the usage of LAPM is important ...

    Authors: Joshua Amo-Adjei, Michael Mutua, Carol Mukiira, Namuunda Mutombo, Sherine Athero, Alex Ezeh and Chimaraoke Izugbara

    Citation: BMC Women's Health 2019 19:26

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  41. Content type: Debate

    Probiotics are live microorganisms that, when administered in adequate amounts, should confer a health benefit to the host. Media sources tend to present probiotics as an appealing health promotion method able...

    Authors: Laura Buggio, Edgardo Somigliana, Alessandra Borghi and Paolo Vercellini

    Citation: BMC Women's Health 2019 19:25

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  42. Content type: Research article

    The family planning component of postabortion care (PAC) is critical, as it helps women to prevent unintended pregnancies and reduce future incidence of life-threatening unsafe abortion. In Tanzania, PAC was r...

    Authors: Colin Baynes, J. Kahwa, G. Lusiola, F. Mwanga, J. Bantambya, L. Ngosso and M. Hiza

    Citation: BMC Women's Health 2019 19:22

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  43. Content type: Research article

    SNF5 is a key protein in regulating cell proliferation and apoptosis in various cancers. However, the physiological roles of SNF5 in Endometrial carcinoma (EC), which is one of the most frequent malignancies o...

    Authors: Shiying Sun, Yi Wu, Kai Zeng and Yue Zhao

    Citation: BMC Women's Health 2019 19:16

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  44. Content type: Research article

    Cesarean scar endometriosis (CSE) is the most common type of abdominal wall endometriosis (AWE). The aim of this study was to systematically identify the clinical features of CSE and recommend precautionary me...

    Authors: Ping Zhang, Yabing Sun, Chen Zhang, Yeping Yang, Linna Zhang, Ningling Wang and Hong Xu

    Citation: BMC Women's Health 2019 19:14

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  45. Content type: Research article

    Because it is difficult to diagnose accurately whether uterine corporeal mesenchymal tumors are benign or malignant before surgery, an understanding of the characteristics of patients with uterine sarcomas occ...

    Authors: Yumi Ishidera, Hiroshi Yoshida, Yuka Oi, Kayo Katayama, Etsuko Miyagi, Hiroyuki Hayashi and Hiroyuki Shigeta

    Citation: BMC Women's Health 2019 19:13

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