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Gynecology, gynecological disease, and reproductive health

Section edited by Aleksandra Gentry-Maharaj, and Zephne van der Spuy

This section considers studies regarding all aspects of gynecology and reproductive health, including cervical cancer, ovarian cancer, fertility, contraception, abortion, menarche, menstruation, and menopause.

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  1. In the Democratic Republic of Congo (DRC), practical and affordable strategies for cervical cancer screening are needed to detect and treat pre-cancerous and cancerous lesions in a timely fashion. This study p...

    Authors: Justin Lussy Paluku, Tamar E. Carter, Miriam Lee and Susan A Bartels

    Citation: BMC Women's Health 2019 19:43

    Content type: Research article

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  2. One of the leading cause of maternal mortality and morbidity is unsafe abortion. Globally 55.7million of abortions occurred each year between 2010 and 2014. In lower resource countries 24.3 million abortions w...

    Authors: Jamuna Tamrakar Sayami

    Citation: BMC Women's Health 2019 19:41

    Content type: Research article

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  3. Obstetric fistula is a hole between the vagina and bladder, and/or between the vagina and rectum, triggered by prolonged obstructed labor. The World Health Organization has estimated that at least 50,000 to 10...

    Authors: Misganaw Animut, Abebe Mamo, Lakew Abebe, Million Abera Berhe, Shifera Asfaw and Zewdie Birhanu

    Citation: BMC Women's Health 2019 19:37

    Content type: Research article

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  4. Vaginal douching is a common practice among women all over the world. Women douche for various reasons, despite evidence indicating the harmful health effects of the practice. There is lack of data on the prac...

    Authors: Florence Assibi Ziba, Vida Nyagre Yakong, Rockson Asaan Asore, Keville Frederickson and Michele Flynch

    Citation: BMC Women's Health 2019 19:32

    Content type: Research article

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  5. Local treatment for cervical intraepithelial neoplasia (CIN) by Loop Electrosurgical Excision Procedure (LEEP) has been correlated with reproductive morbidity, while the cervicovaginal microbiota is also known...

    Authors: Johanna Wiik, Verena Sengpiel, Maria Kyrgiou, Staffan Nilsson, Anita Mitra, Tom Tanbo, Christine Monceyron Jonassen, Tone Møller Tannæs and Katrine Sjøborg

    Citation: BMC Women's Health 2019 19:30

    Content type: Research article

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  6. Heavy menstrual bleeding (HMB) has been shown to have a profound negative impact on women’s quality of life and lead to increases in health care costs; however, data on HMB among Chinese population is still ra...

    Authors: Chengyi Ding, Jing Wang, Yu Cao, Yuting Pan, Xueqin Lu, Weiwei Wang, Lin Zhuo, Qinjie Tian and Siyan Zhan

    Citation: BMC Women's Health 2019 19:27

    Content type: Research article

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  7. The use of long-acting and permanent method (LAPM) for family planning (FP) is of importance to the FP movement. A better understanding of how fertility-related intentions shape the usage of LAPM is important ...

    Authors: Joshua Amo-Adjei, Michael Mutua, Carol Mukiira, Namuunda Mutombo, Sherine Athero, Alex Ezeh and Chimaraoke Izugbara

    Citation: BMC Women's Health 2019 19:26

    Content type: Research article

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  8. Probiotics are live microorganisms that, when administered in adequate amounts, should confer a health benefit to the host. Media sources tend to present probiotics as an appealing health promotion method able...

    Authors: Laura Buggio, Edgardo Somigliana, Alessandra Borghi and Paolo Vercellini

    Citation: BMC Women's Health 2019 19:25

    Content type: Debate

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  9. The family planning component of postabortion care (PAC) is critical, as it helps women to prevent unintended pregnancies and reduce future incidence of life-threatening unsafe abortion. In Tanzania, PAC was r...

    Authors: Colin Baynes, J. Kahwa, G. Lusiola, F. Mwanga, J. Bantambya, L. Ngosso and M. Hiza

    Citation: BMC Women's Health 2019 19:22

    Content type: Research article

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  10. SNF5 is a key protein in regulating cell proliferation and apoptosis in various cancers. However, the physiological roles of SNF5 in Endometrial carcinoma (EC), which is one of the most frequent malignancies o...

    Authors: Shiying Sun, Yi Wu, Kai Zeng and Yue Zhao

    Citation: BMC Women's Health 2019 19:16

    Content type: Research article

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  11. Cesarean scar endometriosis (CSE) is the most common type of abdominal wall endometriosis (AWE). The aim of this study was to systematically identify the clinical features of CSE and recommend precautionary me...

    Authors: Ping Zhang, Yabing Sun, Chen Zhang, Yeping Yang, Linna Zhang, Ningling Wang and Hong Xu

    Citation: BMC Women's Health 2019 19:14

    Content type: Research article

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  12. Because it is difficult to diagnose accurately whether uterine corporeal mesenchymal tumors are benign or malignant before surgery, an understanding of the characteristics of patients with uterine sarcomas occ...

    Authors: Yumi Ishidera, Hiroshi Yoshida, Yuka Oi, Kayo Katayama, Etsuko Miyagi, Hiroyuki Hayashi and Hiroyuki Shigeta

    Citation: BMC Women's Health 2019 19:13

    Content type: Research article

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  13. Polycystic ovarian syndrome (PCOS) is of frequent occurrence in Saudi females and is often associated with obesity, insulin resistance, hypogonadotropic hypogonadism, and infertility. Since these features are ...

    Authors: Maha H. Daghestani, Mazin H. Daghestani, Mamoon H. Daghistani, Geir Bjørklund, Salvatore Chirumbolo and Arjumand Warsy

    Citation: BMC Women's Health 2019 19:10

    Content type: Research article

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  14. Cervical cancer in Saudi Arabia is ranked as the third most frequent gynecological cancer among women. The Pap smear test is a screening test that can be used as a primary prevention tool for cervical cancer, ...

    Authors: Arwa I. Aldohaian, Sulaiman A. Alshammari and Danyah M. Arafah

    Citation: BMC Women's Health 2019 19:6

    Content type: Research article

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  15. Obstetric fistula is an abnormal connection between the vagina and rectum and/or bladder, which leads to continuous urinary or fecal incontinence. It is a serious problem in the world poorest countries, where ...

    Authors: Leltework Yismaw, Kassahun Alemu, Abebaw Addis and Muluneh Alene

    Citation: BMC Women's Health 2019 19:5

    Content type: Research article

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  16. HPV DNA is found in almost 80% of VIN/VaIN. Current management is inadequate, with high recurrence rates. Our objective was to review the literature regarding the role of HPV vaccine in secondary prevention an...

    Authors: Stacey Bryan, Cynthia Barbara, Jane Thomas and Adeola Olaitan

    Citation: BMC Women's Health 2019 19:3

    Content type: Research article

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  17. Cancer screening programs hold much potential for reducing the cervical cancer disease burden in developing countries. The aim of this study was to determine the feasibility of mobile health (mHealth) phone te...

    Authors: Jennifer Moodley, Deborah Constant, Matthys H. Botha, Frederick H. van der Merwe, Amanda Edwards and Mariette Momberg

    Citation: BMC Women's Health 2019 19:2

    Content type: Research article

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  18. To compare potential factors associated with deep infiltrating endometriosis (DIE) versus ovarian endometrioma (OMA) among endometriosis patients in China.

    Authors: Yi Dai, Yingfang Zhou, Xinmei Zhang, Min Xue, Pengran Sun, Jinhua Leng and Charles Chapron

    Citation: BMC Women's Health 2018 18:205

    Content type: Research article

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  19. The purpose of this comprehensive meta-analysis was to assess the association of aldehyde dehydrogenase (ALDH) expression with overall survival (OS) and disease-free survival (DFS)/progression-free survival (P...

    Authors: Yan Xia, Xuemin Wei, Hui Gong and Yunxiang Ni

    Citation: BMC Women's Health 2018 18:199

    Content type: Research article

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  20. Early diagnosis and efficient management of Chronic Endometritis (CE) in patients seeking fertility treatment are two components every practitioner wishes to address. With respect to endometrial restoration, a...

    Authors: Konstantinos Sfakianoudis, Mara Simopoulou, Yorgos Nikas, Anna Rapani, Nikolaos Nitsos, Katerina Pierouli, Athanasios Pappas, Agni Pantou, Christina Markomichali, Michael Koutsilieris and Konstantinos Pantos

    Citation: BMC Women's Health 2018 18:197

    Content type: Case report

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  21. Lifestyle, in particular obesity and smoking has significant impacts on fertility and an important focus for the treatment of reproductive failures is the optimisation of periconceptional lifestyle behaviours....

    Authors: Ka Ying Bonnie Ng, Susan Wellstead, Ying Cheong and Nick Macklon

    Citation: BMC Women's Health 2018 18:196

    Content type: Study protocol

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  22. To investigate the impact of follicular flushing on the number of oocytes retrieved and embryo quality and to determine the optimal number of flushings for poor ovarian responders (PORs) undergoing in vitro fe...

    Authors: Yu Xiao, Yong Wang, Min Wang and Kai Liu

    Citation: BMC Women's Health 2018 18:186

    Content type: Research article

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  23. Individuals with high sexual compulsivity are preoccupied with their sexual desire to such an extent that it interferes with their normal daily life and can inhibit self-control. Previous studies have found a ...

    Authors: Mengyun Luo, Liping Zhu, Yuanyuan Dong, Zezhou Wang, Qiuming Shen, Dandan Mo, Li Du, Zhiruo Zhang and Yong Cai

    Citation: BMC Women's Health 2018 18:181

    Content type: Research article

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  24. To combine results from a randomized controlled study (RCT) and an observational study (OS) to evaluate discontinuation rate of a levonorgestrel-containing intrauterine contraceptive device (LNG IUD) in a real...

    Authors: Tatsiana Vaitsiakhovich, Anna Filonenko, Richard Lynen, Jan Endrikat and Christoph Gerlinger

    Citation: BMC Women's Health 2018 18:180

    Content type: Research article

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  25. The current estimates of the prevalence of primary ovarian insufficiency (POI) are very variable, but are in most studies believed to be around 1%. It is also very likely tat the prevalence of POI differs betw...

    Authors: Katarina Lagergren, Mats Hammar, Elizabeth Nedstrand, Marie Bladh and Gunilla Sydsjö

    Citation: BMC Women's Health 2018 18:175

    Content type: Research article

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  26. We evaluated the effect of transvaginal mesh (TVM) surgery for voiding function and continence using noninvasive examination and questionnaire. The present study aimed to ascertain which categories of patients...

    Authors: Shohei Kawaguchi, Kazutaka Narimoto, Satoko Urata, Masami Takeyama, Yoshifumi Kadono and Atsushi Mizokami

    Citation: BMC Women's Health 2018 18:174

    Content type: Research article

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  27. Vaginal microbicides are a promising means to prevent the transmission of HIV and other sexually transmitted infections, by empowering women to initiate use prophylactically when they perceive themselves to be...

    Authors: Toral Zaveri, Kimberly A Powell, Kate M Guthrie, Alyssa J Bakke, Gregory R Ziegler and John E Hayes

    Citation: BMC Women's Health 2018 18:170

    Content type: Research article

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  28. Morcellation of undiagnosed uterine sarcoma is cause of abdominal/pelvic dissemination, residual tumor and recurrence. In the preoperative evaluation of suspect uterine masses, magnetic resonance imaging (MRI)...

    Authors: Antonio Mollo, Antonio Raffone, Antonio Travaglino, Annalisa Di Cello, Gabriele Saccone, Fulvio Zullo and Giuseppe De Placido

    Citation: BMC Women's Health 2018 18:169

    Content type: Case report

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  29. A unique standardized national dataset on adolescent girls (21 regions) participating in the Italian Health Behaviour in School-aged Children Study (HBSC) was used to investigate the correlation between body m...

    Authors: Giacomo Lazzeri, Claudia Tosti, Andrea Pammolli, Gianmarco Troiano, Alessio Vieno, Natale Canale, Paola Dalmasso, Patrizia Lemma, Alberto Borraccino, Felice Petraglia and Stefano Luisi

    Citation: BMC Women's Health 2018 18:168

    Content type: Research article

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  30. A septate uterus is a uterine anomaly that may affect reproductive outcome, and is associated with an increased risk for miscarriage, subfertility and preterm birth. Resection of the septum is subject of debat...

    Authors: J. F. W. Rikken, C. R. Kowalik, M. H. Emanuel, M. Y. Bongers, T. Spinder, J. H. de Kruif, K. W. M. Bloemenkamp, F. W. Jansen, S. Veersema, A. G. M. G. J. Mulders, A. L. Thurkow, K. Hald, A. Mohazzab, Y. Khalaf, T. J. Clark, M. Farrugia…

    Citation: BMC Women's Health 2018 18:163

    Content type: Study protocol

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  31. Abortion rate in Ukraine is high and the use of effective contraceptive methods is low. Aiming to explore women’s knowledge and attitudes towards modern contraceptive methods, we performed a survey among women...

    Authors: Volodymyr Podolskyi, Kristina Gemzell-Danielsson and Lena Marions

    Citation: BMC Women's Health 2018 18:159

    Content type: Research article

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  32. Induced abortion is one of the most common gynecological procedures in Sweden, but there is still little knowledge about the adverse effects. The aims of this study are to provide an overview of complications ...

    Authors: Isabelle Carlsson, Karin Breding and P.-G. Larsson

    Citation: BMC Women's Health 2018 18:158

    Content type: Research article

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  33. Exposure to domestic violence and abuse (DVA) results in a reduction of women’s use of regular contraceptives. This evidence suggests that women exposed to DVA are more likely to have unprotected sexual interc...

    Authors: Natalia V. Lewis, Theresa H. M. Moore, Gene S. Feder, John Macleod and Penny Whiting

    Citation: BMC Women's Health 2018 18:156

    Content type: Research article

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  34. As HPV is a sexually transmitted virus, men are crucial in the prevention of cervical cancer, but research about men’s awareness on cervical cancer is limited. Therefore, in this study, we investigated men’s a...

    Authors: Hae Won Kim, Duck Hee Kim and Youngji Kim

    Citation: BMC Women's Health 2018 18:155

    Content type: Research article

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  35. Women after menopause increase risk for cardiovascular disease and several factors may be related. The purpose was to study biological and psychosocial factors associated with early cardiovascular damage in pr...

    Authors: Mauricio Sanchez-Barajas, Lorena del Rocio Ibarra-Reynoso, Marco Antonio Ayala-Garcia and Juan Manuel Malacara

    Citation: BMC Women's Health 2018 18:153

    Content type: Research article

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  36. Idiopathic recurrent miscarriage, defined as three or more consecutive miscarriages, is a distressing early pregnancy complication. Although, the etiology of recurrent miscarriage is still unknown, an aberrant...

    Authors: Frida Husseini-Akram, Sally Haroun, Signe Altmäe, Lottie Skjöldebrand-Sparre, Helena Åkerud, Inger Sundström Poromaa, Britt-Marie Landgren and Anneli Stavreus-Evers

    Citation: BMC Women's Health 2018 18:143

    Content type: Research article

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  37. Since the publication over 50 years ago of the alkaline hematin method for quantifying menstrual blood loss (MBL) many new approaches have been developed to assess MBL. The aim of this systematic review is to ...

    Authors: Julia L. Magnay, Shaughn O’Brien, Christoph Gerlinger and Christian Seitz

    Citation: BMC Women's Health 2018 18:142

    Content type: Research article

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  38. Despite the enormous benefits of family planning services, the contraceptive utilization still remains low in Sub-Saharan Africa. There is regional variation in modern contraceptive utilization in Ethiopia. Th...

    Authors: Geta Asrade Alemayehu, Abel Fekadu, Mezgebu Yitayal, Yigzaw Kebede, Solomon Mekonnen Abebe, Tadesse Awoke Ayele, Zemichael Gizaw, Mamo Wubeshet, Kindie Fentahun Muchie, Abebaw Addis Gelagay, Temesgen Azmeraw, Melkamu Birku, Kassahun Alemu, Amare Tariku, Terefe Derso, Adino Tesfahun…

    Citation: BMC Women's Health 2018 18:118

    Content type: Research article

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  39. Female sex workers living with HIV are at increased risk for negative health outcomes and multiple levels of stigma. However, there is limited research on female sex workers living with HIV and even less focus...

    Authors: Dana Cernigliaro, Clare Barrington, Martha Perez, Yeycy Donastorg and Deanna Kerrigan

    Citation: BMC Women's Health 2018 18:117

    Content type: Research article

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  40. The incidence of cervical cancer in Kenya is among the highest in the world. Few Kenyan women are able to access screening, thus fueling the high cervical cancer burden. Self-collected human papilloma Virus (H...

    Authors: Megan Swanson, Saduma Ibrahim, Cinthia Blat, Sandra Oketch, Easter Olwanda, May Maloba and Megan J Huchko

    Citation: BMC Women's Health 2018 18:116

    Content type: Research article

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  41. Laparoscopic surgery is progressing rapidly is becoming the normal route for many abdominal operations, even for major complex surgery. The integrated laparoscopic theatre is a state-of-the-art system in which...

    Authors: Tom K. Holland, Stephen Morris and Alfred Cutner

    Citation: BMC Women's Health 2018 18:112

    Content type: Research article

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  42. Female Sex Workers (FSWs) are predisposed to a broad range of social, sexual and reproductive health problems such as sexually transmitted infections (STIs)/HIV, unintended pregnancy, violence, sexual exploita...

    Authors: Rhoune Ochako, Jerry Okal, Steven Kimetu, Ian Askew and Marleen Temmerman

    Citation: BMC Women's Health 2018 18:105

    Content type: Research article

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  43. Hundreds of millions of women suffer from pelvic floor disorders globally, often in silence. Women in developing countries do not disclose their problems due to associated social stigma or lack of access to se...

    Authors: Merga Dheresa, Alemayehu Worku, Lemessa Oljira, Bizatu Mengiste, Nega Assefa and Yemane Berhane

    Citation: BMC Women's Health 2018 18:95

    Content type: Research article

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