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Table 2 Molecular breast cancer subtypes by tumor histopathology (Total number N = 269)

From: Molecular breast cancer subtypes and therapies in a public hospital of Northeastern Brazil

 

Luminal A

Luminal B

HER2/neu

TN

p

 

N

%

N

%

N

%

N

%

 

Tumor size, cm (T category; T1: ≤ 2.0 cm; T2: > 2.0 cm ≤ 5.0 cm; T3: > 5.0 cm)1

T1

32

52.46

49

41.88

14

35.90

10

22.73

0.0803

T2

26

42.62

57

48.72

22

56.41

31

70.45

T3

3

4,92

11

9.40

3

7.69

3

6.82

Missing

3

 

3

 

0

 

2

  

Lymph node status

Positive

22

43.14

41

40.20

13

41.94

19

51.35

0.7067

Negative

29

56.86

61

59.80

18

58.06

18

48.65

Missing

13

 

18

 

8

 

9

  

Distant metastases

Positive

9

16.36

14

12.73

6

18.18

8

17.78

0.7922

Negative

46

83.64

96

87.27

27

81.82

37

82.22

Missing

9

 

10

 

6

 

1

  

Histological grade

Low (G1)

11

21.57

14

13.59

1

2.94

1

2.86

< 0.0001

Inter. (G2)

38

74.51

76

73.79

21

61.77

22

62.86

High (G3)

2

3.92

13

12.62

12

35.29

12

34.28

Missing

14

 

17

 

5

 

11

  

Ki67 positive cells (%)

Mean

6.05 ± 0.467

36.71 ± 1.819

36.43 ± 4.120

50.38 ± 4.691

< 0.0001

  1. 1Pair wise comparison of Luminal A and TN: p = 0.0088; Luminal B and TN: p = 0.0448.