Skip to main content

Advertisement

Table 1 Characteristics of premenstrual syndrome cases and controls at the time of blood collection, NHS2 PMS Sub-study

From: Plasma 25-hydroxyvitamin D and risk of premenstrual syndrome in a prospective cohort study

Characteristic PMS cases n = 401 Controls n = 401 P value
  Mean (SD) Mean (SD)  
Age (years) 40.6 (4.0) 40.7 (3.8) 0.94
Body mass index (kg/m2) 25.7 (5.8) 25.4 (5.8) 0.50
Body mass index at age 18 (kg/m2) 21.5 (3.4) 21.4 (3.5) 0.81
Age at menarche (years) 12.5 (1.4) 12.4 (1.5) 0.45
Number of full term pregnancies 2.0 (1.2) 2.0 (1.3) 0.43
Age at first birth (years)* 26.2 (4.2) 26.7 (4.1) 0.11
Physical activity (MET/wk) 18.7 (19.4) 20.0 (20.8) 0.36
Alcohol intake (grams/day) 4.6 (6.8) 3.7 (6.5) 0.05
  % %  
White race 96.0 98.8 0.02
Mother had > high school education 31.9 39.9 0.02
More than 5 moles on lower leg† 15.5 17.0 0.57
Low UV radiation index region of US 22.2 26.0 0.22
Current smoker 11.2 4.7 <0.001
Former smoker 30.7 15.7 <0.001
Tubal ligation 31.1 25.2 0.06
Significant childhood trauma 18.1 5.6 <0.001
Antidepressant use& 14.7 6.2 <0.001
Ever used oral contraceptives 86.5 77.3 <0.001
Calcium/vitamin D supplement use 41.4 39.9 0.67
B vitamin supplement use 17.7 10.0 0.002
Regular multivitamin use 48.9 44.1 0.18
Biomarkers Mean (SD) Mean (SD)  
25-hydroxyvitamin D (nmol/L) 66.5 (20.5) 64.8 (19.9) 0.24
Total calcium (mg/dL) 9.74 (0.39) 9.72 (0.38) 0.64
Intact Parathyroid hormone (pg/mL) 31.2 (11.5) 31.1 (11.6) 0.92
  1. *Among parous women (n = 326 controls, 340 cases).
  2. †At baseline; a measure of light skin tone.
  3. &Use before diagnosis (cases).