Table 4 Multivariate analysis of risk factors and HER-2/neu overexpression according to ER¹ status.

ER + cases

Body mass index(>29 kg/m²)

5.59 (2.58–12.13)

2.84 (1.52–5.32)

NS

Age at 1st pregnancy (≥ 23 years)

2.09 (0.97–4.53)

NS

NS

First degree family history (positive)

NS

2.18 (0.92–5.14)

NS

Abortion or miscarriage (ever)

0.44 (0.20–0.95)

0.56 (0.32–0.99)

NS

ER – cases

Body mass index(>29 kg/m²)

5.33 (2.59–10.94)

2.41 (1.15–5.04)

2.46 (0.97–6.21)

Age at 1st pregnancy (≥ 23 years)

2.37 (1.08–5.18)

1.78 (0.93–3.42)

NS

First degree family history (positive)

NS

2.72 (1.05–7.07)

NS

Age of menopause (>50 years)

NS

2.05 (1.10–3.79)

NS

Parity (1–2 children)

NS

2.38 (1.21–4.67)

NS