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Table 2 Prevalence and determinants of current MHT use in the two surveys conducted before (1997–1999) and after (2003–2004) the publication of EPT-WHI trial results

From: Differences in Menopausal Hormone Therapy Use among Women in Germany between 1998 and 2003

  Prevalence % Difference % OR (95% CI)
  1997–1999 2003–2004 Absolute Relative 1997–1999 2003–2004
Age, years       
   40–49 10.7 3.9 -6.8 -63.6 0.20(0.15–0.27) 0.14(0.09–0.21)
   50–59 36.3 21.3 -15.0 -41.3 1(Reference) 1(Reference)
   60–69 20.3 18.5 -1.8 -8.9 0.56(0.42–0.76) 0.78(0.55–1.09)
   70–79 5.7 3.2 -2.5 -43.9 0.13(0.07–0.23) 0.14(0.07–0.31)
Region       
   West Germany 18.4 10.7 -7.7 -41.8 1.73(1.33–2.25) 1.74(1.15–2.64)
   East Germany 11.9 7.9 -4.0 -33.6 1(Reference) 1(Reference)
BMI       
   < 25 kg/m 2 20.5 9.8 -10.7 -52.2 1.79(1.28–2.51) 1.38(0.90–2.11)
   25–30 kg/m 2 18.8 12.3 -6.5 -34.6 1.70(1.24–2.34) 1.42(0.96–2.10)
   > = 30 kg/m 2 10.0 7.5 -2.5 -25.0 1(Reference) 1(Reference)
Social status       
   Lower 9.3 8.1 -1.2 -12.9 1(Reference) 1(Reference)
   Intermediate 20.2 11.1 -9.1 -45.0 1.87(1.37–2.55) 0.85(0.61–1.18)
   Upper 25.3 9.3 -16.0 -63.2 1.96(1.35–2.86) 0.73(0.48–1.10)
Smoking status       
   Smoker 18.8 10.9 -7.9 -42.0 1(Reference) 1(Reference)
   Ex-smoker 21.5 8.4 -13.1 -60.9 1.00(0.68–1.46) 0.91(0.60–1.38)
   Non-smoker 16.1 10.5 -5.6 -34.8 0.86(0.64–1.17) 1.00(0.70–1.43)
Physical activity       
   0 hrs/wk 13.5 8.5 -5.0 -37.0 1(Reference) 1(Reference)
   0–1 hrs/wk 21.6 9.9 -11.7 -54.2 1.49(1.06–2.10) 1.15(0.71–1.88)
   1–2 hrs/wk 22.0 11.1 -10.9 -49.5 1.29(0.94–1.76) 0.85(0.58–1.23)
   > 2 hrs/wk 25.6 12.7 -12.9 -50.4 1.56(1.10–2.21) 1.02(0.71–1.48)
Pre-existing medical conditions (yes vs. no)       
Diabetes 6.4 3.5 -2.9 -45.3 0.74(0.41–1.33) 0.42(0.21–0.87)
Hypertension 14.3 9.9 -4.4 -30.8 1.06(0.80–1.39) 1.07(0.78–1.47)
Hyperlipidemia 17.3 11.4 -5.9 -34.1 1.03(0.79–1.33) 1.13(0.84–1.52)
CVD 9.4 10.1 +0.7 +7.4 0.80(0.51–1.25) 1.02(0.63–1.64)
  1. Odds ratios (OR) and 95% confidence intervals (CI) were obtained from survey specific multivariable regression models with current MHT as the dependent variable. Explanatory variables included age (10-year age groups) as well as socio-demographic, behavioural and medical characteristics as shown above.
  2. EPT-WHI = combined estrogen plus progestin therapy arm of the Women's Health Initiative randomized controlled trial; BMI = Body mass index; CVD = cardiovascular disease; hr(s)/wk = hour(s)/week.