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Table 2 Prevalence and determinants of current MHT use in the two surveys conducted before (1997–1999) and after (2003–2004) the publication of EPT-WHI trial results

From: Differences in Menopausal Hormone Therapy Use among Women in Germany between 1998 and 2003

 

Prevalence %

Difference %

OR (95% CI)

 

1997–1999

2003–2004

Absolute

Relative

1997–1999

2003–2004

Age, years

      

   40–49

10.7

3.9

-6.8

-63.6

0.20(0.15–0.27)

0.14(0.09–0.21)

   50–59

36.3

21.3

-15.0

-41.3

1(Reference)

1(Reference)

   60–69

20.3

18.5

-1.8

-8.9

0.56(0.42–0.76)

0.78(0.55–1.09)

   70–79

5.7

3.2

-2.5

-43.9

0.13(0.07–0.23)

0.14(0.07–0.31)

Region

      

   West Germany

18.4

10.7

-7.7

-41.8

1.73(1.33–2.25)

1.74(1.15–2.64)

   East Germany

11.9

7.9

-4.0

-33.6

1(Reference)

1(Reference)

BMI

      

   < 25 kg/m 2

20.5

9.8

-10.7

-52.2

1.79(1.28–2.51)

1.38(0.90–2.11)

   25–30 kg/m 2

18.8

12.3

-6.5

-34.6

1.70(1.24–2.34)

1.42(0.96–2.10)

   > = 30 kg/m 2

10.0

7.5

-2.5

-25.0

1(Reference)

1(Reference)

Social status

      

   Lower

9.3

8.1

-1.2

-12.9

1(Reference)

1(Reference)

   Intermediate

20.2

11.1

-9.1

-45.0

1.87(1.37–2.55)

0.85(0.61–1.18)

   Upper

25.3

9.3

-16.0

-63.2

1.96(1.35–2.86)

0.73(0.48–1.10)

Smoking status

      

   Smoker

18.8

10.9

-7.9

-42.0

1(Reference)

1(Reference)

   Ex-smoker

21.5

8.4

-13.1

-60.9

1.00(0.68–1.46)

0.91(0.60–1.38)

   Non-smoker

16.1

10.5

-5.6

-34.8

0.86(0.64–1.17)

1.00(0.70–1.43)

Physical activity

      

   0 hrs/wk

13.5

8.5

-5.0

-37.0

1(Reference)

1(Reference)

   0–1 hrs/wk

21.6

9.9

-11.7

-54.2

1.49(1.06–2.10)

1.15(0.71–1.88)

   1–2 hrs/wk

22.0

11.1

-10.9

-49.5

1.29(0.94–1.76)

0.85(0.58–1.23)

   > 2 hrs/wk

25.6

12.7

-12.9

-50.4

1.56(1.10–2.21)

1.02(0.71–1.48)

Pre-existing medical conditions (yes vs. no)

      

Diabetes

6.4

3.5

-2.9

-45.3

0.74(0.41–1.33)

0.42(0.21–0.87)

Hypertension

14.3

9.9

-4.4

-30.8

1.06(0.80–1.39)

1.07(0.78–1.47)

Hyperlipidemia

17.3

11.4

-5.9

-34.1

1.03(0.79–1.33)

1.13(0.84–1.52)

CVD

9.4

10.1

+0.7

+7.4

0.80(0.51–1.25)

1.02(0.63–1.64)

  1. Odds ratios (OR) and 95% confidence intervals (CI) were obtained from survey specific multivariable regression models with current MHT as the dependent variable. Explanatory variables included age (10-year age groups) as well as socio-demographic, behavioural and medical characteristics as shown above.
  2. EPT-WHI = combined estrogen plus progestin therapy arm of the Women's Health Initiative randomized controlled trial; BMI = Body mass index; CVD = cardiovascular disease; hr(s)/wk = hour(s)/week.