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Table 2 Multivariate logistic regression of demographic predictors of anticipated uptake of genetic testing for ovarian cancer risk

From: Genetic testing and personalized ovarian cancer screening: a survey of public attitudes

Variable

Probable/definite uptake of OC genetic testing if offered by NHS

Probable/definite uptake of OC genetic testing if it also informs about BC risk

Probable/definite uptake of OC genetic testing with potential for surgery

Probable/definite uptake of OC screening if offered by the NHS

Good/very good idea varying frequency of OC cancer screening by personal risk

N = 829

OR

95 % CI

p-value

OR

95 % CI

p-value

OR

95 % CI

p-value

OR

95 % CI

p-value

OR

95 % CI

p-value

Age (trend)

0.99

0.98-1.02

0.153

0.99

0.98-1.00

0.081

1.01

1.00-1.01

0.028

1.00

0.99-1.00

0.924

1.00

0.99-1.01

0.881

Ethnicity

Ethnic minority

1

  

1

  

1

  

1

  

1

  

White

1.67

0.98-2.83

0.057

1.62

0.95-2.75

0.073

2.14

1.25-3.66

0.006

1.85

1.06-3.23

0.028

1.51

0.87-2.60

0.136

Education

Below university

1

  

1

  

1

  

1

  

1

  

University

0.67

0.49-0.94

0.009

0.76

0.56-1.03

0.078

0.93

0.69-1.27

0.938

1.15

0.88-1.79

0.204

2.22

1.57-3.14

<0.001

Marital status

Sgl/wid/div

1

  

1

  

1

  

1

  

1

  

Married/cohab

1.24

0.95-1.62

0.103

1.06

0.80-1.39

0.664

1.41

1.08-1.84

0.012

1.35

1.00-1.83

0.050

1.08

0.82-1.43

0.568

  1. Abbreviations: Sgl single, wid widowed, div divorced, cohab cohabiting
  2. Analyses are mutually adjusted for age (modelled as continuous variable), ethnicity, education and marital status (modelled as binary variables)
  3. BOLD significant after adjustment for multiple testing p < 0.01